Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.1.174: glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase

This is an abbreviated version!
For detailed information about glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.174

Reaction

UDP-N-acetyl-alpha-D-galactosamine
+
[protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine
=
UDP
 +
[protein]-3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine

Synonyms

acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-chondroitin, I, ChGn-1, ChGn-2, chondroitin beta1,4-N-acetylgalactosaminyltransferase-1, chondroitin galactosaminyltransferase, chondroitin N-acetylgalactosaminyltransferase-1, chondroitin N-acetylgalactosaminyltransferase-2, chondroitin sulfate beta-1,4-N-acetylgalactosaminyltransferase-1 ChGn-1, chondroitin sulfate N-acetylgalactosaminyltransferase 1, chondroitin sulfate N-acetylgalactosaminyltransferase 2, chondroitin sulfate N-acetylgalactosaminyltransferase-1, chondroitin sulfate N-acetylgalactosaminyltransferase-2, chondroitin sulfate synthase 1, chondroitin sulfate synthase-1, chondroitin sulphate N-acetylgalactosaminyl-transferase-1, chondroitin sulphate N-acetylgalactosaminyltransferase 1, CHSY1, CS N-acetylgalactosaminyltransferase 1, CS N-acetylgalactosaminyltransferase-1, CSGal-NACT-1, CSGalNAcT-1, CSGalNAcT1, CSGALNACT2, CSS1, GalNAcT-I, GalNAcT-II, glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase, More, N-acetylgalactosamineT-II, N-acetylgalactosaminyltransferase I, uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.174 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase

Inhibitors

Inhibitors on EC 2.4.1.174 - glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(E)-2-hydroxy-3-isopentyl-4-methoxy-6-styrylbenzoic acid
-
(E)-2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-(2-phenylprop-1-enyl)benzoic acid
-
(E)-2-hydroxy-4-methoxy-3-prenyl-6-(2-(thiophen-2-yl)vinyl)-benzoic acid
-
(E)-3-(3,7-dimethylocta-2,6-dienyl)-2-hydroxy-4-methoxy-6-phenethylbenzoic acid
-
(E)-3-c-6-hydroxy-4-methoxy-5-prenyl-2-styrylbenzoic acid
-
(E)-3-methoxy-4-(3-methylbut-2-enyl)-5-styrylphenol
i.e. longistyline C
(E)-6-(2-chlorostyryl)-2-hydroxy-4-methoxy-3-prenylbenzoic acid
-
(E)-6-(2-methylstyryl)-2-hydroxy-4-methoxy-3-prenylbenzoic acid
-
(E)-6-(3-methylstyryl)-2-hydroxy-4-methoxy-3-prenylbenzoic acid
-
(E)-6-(4-fluorostyryl)-2-hydroxy-4-methoxy-3-prenylbenzoic acid
-
(E)-6-(4-hydroxystyryl)-2-hydroxy-4-methoxy-3-prenylbenzoic acid
-
(E)-6-(4-methylstyryl)-2-hydroxy-4-methoxy-3-prenylbenzoic acid
-
(E)-6-(but-1-enyl)-2-hydroxy-4-methoxy-3-prenylbenzoic acid
-
(E)-ethyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-styrylbenzoate
-
(E)-isopropyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-styrylbenzoate
-
(E)-methyl 2-hydroxy-3-isopentyl-4-methoxy-6-styrylbenzoate
-
(E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-(2-phenylprop-1-enyl)benzoate
-
(E)-methyl 2-hydroxy-4-methoxy-3-prenyl-6-(2-(thiophen-2-yl)-vinyl)benzoate
-
(E)-methyl 6-(2-chlorostyryl)-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-methyl 6-(2-methylstyryl)-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-methyl 6-(3-methylstyryl)-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-methyl 6-(4-(tert-butyldimethylsilyloxy)styryl)-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-methyl 6-(4-fluorostyryl)-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-methyl 6-(4-hydroxystyryl)-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-methyl 6-(4-methylstyryl)-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-methyl 6-(but-1-enyl)-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-methyl 6-styryl-2-hydroxy-4-methoxy-3-prenylbenzoate
-
(E)-N-cyclopropyl-2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-styrylbenzamide
-
(E)-tert-butyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-styrylbenzoate
-
2-hydroxy-3-isopentyl-4-methoxy-6-phenethylbenzoic acid
-
2-hydroxy-4-methoxy-3-prenyl-6-((1E,3E)-4-phenylbuta-1,3-dienyl)benzoic acid
-
2-hydroxy-4-methoxy-3-prenyl-6-phenethylbenzoic acid
-
brefeldin A
-
cajanine
cajanine is a stilbenic component isolated from Cajanus cajan, it is identified as a potent hepatitis C virus (HCV) inhibitor by phenotypic screening with EC50 of 0.00317 mM. Cajanine inhibits HCV infection by targeting cellular CSGalNAcT-1 protein destabilizing the protein. Cajanine does not inhibit HCV replication at the replicative steps of HCV life cycle. CSGalNAcT-1 is important to support HCV replication at the early stage. Structure-activity relationships and the mechanism of action, and analysis of cajanine derivatives, EC50 values, overview. Cajanine might inhibit HCV replication at early steps of the viral life cycle via downregulating of cellular CSGalNAcT-1
longistyline A
-
methyl 2-hydroxy-4-methoxy-3-prenyl-6-((1E,3E)-4-phenylbuta-1,3-dienyl)benzoate
-
methyl 2-hydroxy-4-methoxy-3-prenyl-6-phenethylbenzoate
-
additional information
-