2.4.1.175: glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase

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For detailed information about glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase, go to the full flat file.

Reaction

Synonyms

AcbD, acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-chondroitin, II, ApCS, bifunctional CS synthase, ChGn-1, ChGn-2, chondroitin galactosaminyltransferase, chondroitin N-acetylgalactosaminyltransferase-1, chondroitin N-acetylgalactosaminyltransferase-2, chondroitin polymerase, chondroitin sulfate beta-1,4-N-acetylgalactosaminyltransferase-1, chondroitin sulfate glucuronyltransferase, chondroitin sulfate glycosyltransferase, chondroitin sulfate N-acetylgalactosaminyltransferase-1, chondroitin sulfate N-acetylgalactosaminyltransferase-2, chondroitin sulfate synthase 1, chondroitin sulfate synthase-1, chondroitin sulfate synthase-2, chondroitin sulfate synthase-2/chondroitin polymerizing factor, chondroitin sulfate synthase-3, chondroitin synthase, chondroitin synthase 1, chondroitin synthase-1, chondroitin synthase-2, chondroitin synthase-3, CHPF, ChSy, ChSy-1, ChSy-2, ChSy-3, CHSY1, CpCS, Cpha266_2341, CS glycosyltransferase, CS N-acetylgalactosaminyltransferase-1, CS synthase 1, CS synthase-1, CSGalNAcT-2, CSGlcA-T, CSS1, CSS2, CSS3, GalNAc-T, glucuronyl-N-acetylgalactosaminylproteoglycan beta1,4-N-acetylgalactosaminyltransferase, K4CP, More, N-acetylgalactosaminyltransferase II, UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferasec II

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.175 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase

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Results	in table
1	Activating Compound
121	AA Sequence
6	Application
1	CAS Registry Number
27	Cloned(Commentary)
1	Crystallization (Commentary)
30	Disease/ Diagnostics
4	Expression
38	General Information
4	General Stability
7	Inhibitors
1	kcat/KM [mM/s]
8	KM Value [mM]
22	Localization
19	Metals/Ions
4	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
57	Organism
5	Pathway
6	PDB ID
13	pH Optimum
2	Posttranslational Modification
15	Protein Variants
9	Purification (Commentary)
3	Reaction
1	Reaction Type
46	Reference
147	Source Tissue
13	Specific Activity [micromol/min/mg]
1	Storage Stability
148	Substrates and Products (Substrate)
7	Subunits
112	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
1	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 2.4.1.175 - glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase

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ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

additional information

Homo sapiens

Q8IZ52

chondroitin polymerizing factor (ChPF) is required for chondroitin polymerizing activity of mammalian ChSy. Chondroitin polymerization is not demonstrated in vitro using the recombinant enzyme

659218

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