2.4.1.206: lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase This is an abbreviated version! For detailed information about lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, go to the full flat file .
Word Map on EC 2.4.1.206
Reaction
UDP-N-acetyl-alpha-D-glucosamine +
beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide =
UDP +
N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
Synonyms acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-lactosylceramide beta-, beta1,3 N-acetylglucosaminyltransferase GlcNAc(beta1,3)Gal(beta1,4)Glc-ceramide synthase, beta1,3-N-acetylglucosaminyltransferase-2, beta1-3-N-acetylglucosaminyltransferase, beta3Gn-T2, beta3Gn-T5, beta3GnT5, GlcNAc transferase, LA2 synthase, LacCer(beta1,3)N-acetylglucosaminyltransferase, lactosylceramide beta-acetylglucosaminyltransferase, lactosylceramide: N-acetylglucosaminyltransferase, lactosylceramide:N-acetylglucosaminyltransferase, lactotriaosylceramide synthase, Lc2Cer-Glc-NAc-Tr, Lc3 synthase, Lc3 synthase/bGn-T5, UDP-GlcNAc:lactosylceramide beta1,3-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase
ECTree
Disease
Disease on EC 2.4.1.206 - lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase
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Breast Neoplasms
Oncodevelopmental expression of--GlcNAc beta 1-6Man alpha 1-6Man beta 1--branched asparagine-linked oligosaccharides in murine tissues and human breast carcinomas.
Carcinoma
Helicobacter pylori induces beta3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x.
Carcinoma, Hepatocellular
Elevated activity of N-acetylglucosaminyltransferase V in human hepatocellular carcinoma.
Glioma
GMab-1, a high-affinity anti-3'-isoLM1/3',6'-isoLD1 IgG monoclonal antibody, raised in lacto-series ganglioside-defective knockout mice.
Infections
Helicobacter pylori induces beta3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x.
Infections
Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains.
Neoplasm Metastasis
Organization of the human N-acetylglucosaminyltransferase V gene.
Neoplasms
Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis.
Neoplasms
Organization of the human N-acetylglucosaminyltransferase V gene.
Neoplasms
Strong antibody reaction against glycosphingolipids injected in liposome-embedded forms in beta3GN-T5 knockout mice.
Neuroblastoma
Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family.
Salmonella Infections
Arginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium.
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