2.4.1.208: diglucosyl diacylglycerol synthase (1,2-linking)

This is an abbreviated version!
For detailed information about diglucosyl diacylglycerol synthase (1,2-linking), go to the full flat file.

Reaction

Synonyms

1,2-diacylglycerol-3-alpha-glucosyl transferase, DGlcDAG synthase, diglucosyldiacylglycerol synthase, glucosyltransferase, uridine diphosphoglucose-monoglucosyldiacylglycerol, MgGlcDAG (1->2) glucosyltransferase, monoglucosyl diacylglycerol (1->2) glucosyltransferase, monoglucosyldiacylglycerol glucosyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.208 diglucosyl diacylglycerol synthase (1,2-linking)

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Results	in table
29	Activating Compound
33	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
1	General Stability
6	Inhibitors
2	KM Value [mM]
3	Localization
3	Metals/Ions
8	Natural Substrates/ Products (Substrates)
34	Organism
3	Pathway
2	pH Optimum
1	Purification (Commentary)
3	Reaction
1	Reaction Type
12	Reference
1	Renatured (Commentary)
1	Specific Activity [micromol/min/mg]
24	Substrates and Products (Substrate)
10	Synonyms
1	Systematic Name

Natural Substrates Products

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Natural Substrates Products on EC 2.4.1.208 - diglucosyl diacylglycerol synthase (1,2-linking)

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol

1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1-2)-O-alpha-D-glucopyranosyl)sn-glycerol + UDP

2 entries

UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol

UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-glucopyranosyl)-sn-glycerol

4 entries

additional information

?

-

2 entries

UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol

1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1-2)-O-alpha-D-glucopyranosyl)sn-glycerol + UDP

Acholeplasma laidlawii

-

enzyme is involved in biosynthesis of phosphoglucolipids and has a regulatory function together with 1,2-diacylglycerol-3-glucosyltransferase, EC 2.4.1.157, overview

661626

-

-

ir

UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol

1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1-2)-O-alpha-D-glucopyranosyl)sn-glycerol + UDP

Acholeplasma laidlawii A-EF22

-

enzyme is involved in biosynthesis of phosphoglucolipids and has a regulatory function together with 1,2-diacylglycerol-3-glucosyltransferase, EC 2.4.1.157, overview

661626

-

-

ir

UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol

UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-glucopyranosyl)-sn-glycerol

Acholeplasma laidlawii

-

at physiological concentrations of phosphatidylglycerol different nonlamellar-promoting pertubants can strongly enhance the synthesis of diglycosyldiacylglycerol in relation to their nonbilayer propensities

488885

-

488885

?

UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol

UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-glucopyranosyl)-sn-glycerol

Acholeplasma laidlawii

-

modulation of the activity by non-bilayer-forming lipids

488886

-

488886

?

UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol

UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-glucopyranosyl)-sn-glycerol

Staphylococcus aureus

-

enzyme provides glycolipid for lipoteichoic acid assembly

488889

-

488889

?

UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol

UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-glucopyranosyl)-sn-glycerol

Staphylococcus aureus RN4220

-

enzyme provides glycolipid for lipoteichoic acid assembly

488889

-

488889

?

additional information

?

-

Acholeplasma laidlawii

-

bilayer binding by the enzyme, overview, the enzyme is made from 1,2-diacylglycerol-3-glucosyltransferase, EC 2.4.1.157, in membranes with more unsaturated or longer acyl chains, increased temperature or increased amount of cholesterol

661626

-

-

?

additional information

?

-

Acholeplasma laidlawii A-EF22

-

bilayer binding by the enzyme, overview, the enzyme is made from 1,2-diacylglycerol-3-glucosyltransferase, EC 2.4.1.157, in membranes with more unsaturated or longer acyl chains, increased temperature or increased amount of cholesterol

661626

-

-

?