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2.4.1.218: hydroquinone glucosyltransferase

This is an abbreviated version!
For detailed information about hydroquinone glucosyltransferase, go to the full flat file.

Reaction

UDP-glucose
+
hydroquinone
=
UDP
+
hydroquinone-O-beta-D-glucopyranoside

Synonyms

arbutin synthase, arbutin synthetase, AS, glucosyltransferase, uridine diphosphoglucose-hydroquinone, hydroquinone glucosyl transferase, hydroquinone O-glucosyltransferase, hydroquinone:O-glucosyltransferase, More, uridine diphosphate-glucose:hydroquinone glucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.218 hydroquinone glucosyltransferase

Engineering

Engineering on EC 2.4.1.218 - hydroquinone glucosyltransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
A204V
site-directed mutagenesis, mutant shows slightly reduced activity compared to the wild-type enzyme
E368A
site-directed mutagenesis, mutant shows reduced activity compared to the wild-type enzyme
E368D
site-directed mutagenesis, mutant shows reduced activity compared to the wild-type enzyme
H360E
site-directed mutagenesis, mutant shows about 4000fold reduced activity compared to the wild-type enzyme
H360K
site-directed mutagenesis, mutant shows about 1000fold reduced activity compared to the wild-type enzyme
H360R
site-directed mutagenesis, mutant shows about 1000fold reduced activity compared to the wild-type enzyme
L86I
site-directed mutagenesis, mutant shows slightly reduced activity compared to the wild-type enzyme
additional information