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2.4.1.225: N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase

This is an abbreviated version!
For detailed information about N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.225

Reaction

UDP-alpha-D-glucuronate
+
N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan
=
UDP
+
beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan

Synonyms

diphosphoglucuronate:oligosaccharide uridine glucuronosyltransferase, exostosin, exostosin-1, exostosin-2, Exostosin1, Exostosin2, exotose-2, EXT-1, EXT-2, EXT-3, EXT1, EXT2, EXTL3, extosin, gene EXTL1 glycosyltransferase, gene EXTL2 glycosyltransferase, glucuronic acid/N-acetylglucosamine co-polymerase-1, glucuronosyltransferase, heparan glucuronosyltransferase II, heparan sulfate co-polymerase, heparan sulfate glucuronosyltransferase, heparan sulfate synthesis enzyme, N-acetylglucosaminylproteoglycan beta-1,4-glucuronosyltransferase, RIB-1, RIB-2, sister of tout velu, sister of tout-velu, sotv, tout velu, tout-velu, ttv, UDP-glucuronate:oligosaccharide

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.225 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase

Substrates Products

Substrates Products on EC 2.4.1.225 - N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
K5 heptasaccharide + UDP-alpha-D-glucuronate
?
show the reaction diagram
UDP-alpha-D-glucuronate + N-acetyl-alpha-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-proteoglycan
UDP + beta-glucuronosyl-(1-4)-N-acetyl-alpha-D-glucosaminyl-(1-4)-beta-D-glucuronosyl-proteoglycan
show the reaction diagram
UDP-N-acetyl-D-glucosamine + alpha-D-glucuronosyl-(1-4)-N-acetylglucoside
UDP + alpha-N-acetyl-D-glucosaminyl-alpha-D-glucuronosyl-(1-4)-N-acetylglucoside
show the reaction diagram
additional information
?
-