2.4.1.227: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase, go to the full flat file.

Reaction

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol

beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol

Synonyms

acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-acetylmuramoylpentapeptide pyrophospholipid, gene murG enzyme, gene murG proteins, HyMurG, Lipid I acetylglucosaminyltransferase, MsmegMurG, MurG, MurG glycosyltransferase, MurG transferase, peptidoglycan glycosyltransferase, proteins, gene murG, translocase II, UDP-acetylglucosamine-acetylmuramoylpentapeptide pyrophospholipid acetylglucosaminyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.227 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

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Results	in table
9	Activating Compound
40181	AA Sequence
8	Application
1	CAS Registry Number
12	Cloned(Commentary)
2	Crystallization (Commentary)
18	General Information
1	General Stability
17	IC50 Value
71	Inhibitors
44	KM Value [mM]
20	Localization
2	Metals/Ions
8	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
33	Organism
9	Pathway
4	PDB ID
4	pH Optimum
1	pH Range
20	Protein Variants
9	Purification (Commentary)
2	Reaction
4	Reaction Type
32	Reference
23	Specific Activity [micromol/min/mg]
3	Storage Stability
45	Substrates and Products (Substrate)
6	Subunits
40	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
18	Turnover Number [1/s]

KM Value

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KM Value on EC 2.4.1.227 - undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase

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1.5

2'-dUDP-N-acetyl-alpha-D-glucosamine

Escherichia coli

P17443

488977

0.0028 - 0.037

biotin-labelled lipid I analogue

2 entries

0.036 - 0.044

biotinylated citronellyl-lipid I

3 entries

0.053

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-(6E,10E,14Z)-2,6,10,14-tetramethyl-hexadeca-2,6,10,14-tetraene

Escherichia coli

pH 7.9, 37°C

658448

0.047

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-(7S)-2,7-dimethyloct-2-ene

Escherichia coli

pH 7.9, 37°C

658448

0.024

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-p-nitrophenol

Escherichia coli

pH 7.9, 37°C

658448

0.022

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphobutane

Escherichia coli

pH 7.9, 37°C

658448

0.029

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphododecane

Escherichia coli

pH 7.9, 37°C

658448

0.052

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoicosane

Escherichia coli

pH 7.9, 37°C

658448

0.039

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphotetradecane

Escherichia coli

pH 7.9, 37°C

658448

0.02

Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol

Escherichia coli

pH 7.9, 37°C

658448

0.0028

MurNAc(Nepsilon-dansylpentapeptide)-pyrophosphoryl (R,S)-alpha-dihydroheptaprenol

Escherichia coli

488978

0.0028 - 0.011

MurNAc(Neta-dansylpentapeptide)-diphosphoryl (R,S-alpha-dihydroheptaprenol)

9 entries

0.553

synthetic substrate analogue 2

Escherichia coli

10 carbon citronellyl derivative

488976

0.053

synthetic substrate analogue 7

2 entries

0.0098 - 1.03

UDP-GlcNAc

10 entries

0.045 - 0.15

UDP-N-acetylglucosamine

6 entries

additional information

Escherichia coli

continous fluorescence coupled enzyme assay method

658448