Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.1.244: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase

This is an abbreviated version!
For detailed information about N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.244

Reaction

UDP-N-acetyl-alpha-D-galactosamine
+
N-acetyl-beta-D-glucosaminyl group
=
UDP
 +
N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group

Synonyms

B4GALNT3, beta 1,4-N-acetylgalactosaminyltransferase-A, beta1,4-N-acetylgalactosaminyltransferase, beta1,4-N-acetylgalactosaminyltransferase II, beta1,4-N-acetylgalactosaminyltransferase III, beta1,4-N-acetylgalactosaminyltransferase IV, beta1,4-N-acetylgalactosaminyltransferase-III, beta4GalNAc-T3, beta4GalNAc-T4, beta4GalNAcT, beta4GalNAcT-II, beta4GalNAcTA, beta4GalNAcTB, N,N'-diacetyllactosediamine synthase, N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1, N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.244 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase

Reference

topprint

Reference on EC 2.4.1.244 - N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Gotoh, M.; Sato, T.; Kiyohara, K.; Kameyama, A.; Kikuchi, N.; Kwon, Y.D.; Ishizuka, Y.; Iwai, T.; Nakanishi, H.; Narimatsu, H.
Molecular cloning and characterization of beta1,4-N-acetylgalactosaminyltransferases IV synthesizing N,N'-diacetyllactosediamine
FEBS Lett.
562
134-140
2004
Homo sapiens (Q76KP1), Homo sapiens
Manually annotated by BRENDA team
Haines, N.; Irvine, K.D.
Functional analysis of Drosophila beta1,4-N-acetylgalactosaminyltransferases
Glycobiology
15
335-346
2005
Drosophila melanogaster, Drosophila melanogaster (Q7KN92)
Manually annotated by BRENDA team
Ikehara, Y.; Sato, T.; Nakamura, S.; Gotoh, M.; Ikehara, S.K.; Kiyohara, K.; Aoki, C.; Iwai, T.; Nakanishi, H.; Hirabayashi, J.; Tatematsu, M.; Narimatsu, H.
Apical Golgi localization of N,N'-diacetyllactosediamine synthase, beta4GalNAc-T3, is responsible for LacdiNAc expression on gastric mucosa
Glycobiology
16
777-785
2006
Homo sapiens
Manually annotated by BRENDA team
Sato, T.; Gotoh, M.; Kiyohara, K.; Kameyama, A.; Kubota, T.; Kikuchi, N.; Ishizuka, Y.; Iwasaki, H.; Togayachi, A.; Kudo, T.; Ohkura, T.; Nakanishi, H.; Narimatsu, H.
Molecular cloning and characterization of a novel human beta1,4-N-acetylgalactosaminyltransferase, beta4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, GalNAc beta1-4GlcNAc
J. Biol. Chem.
278
47534-47544
2003
Homo sapiens (Q6L9W6), Homo sapiens
Manually annotated by BRENDA team
Sasaki, N.; Yoshida, H.; Fuwa, T.J.; Kinoshita-Toyoda, A.; Toyoda, H.; Hirabayashi, Y.; Ishida, H.; Ueda, R.; Nishihara, S.
Drosophila beta1,4-N-acetylgalactosaminyltransferase-A synthesizes the LacdiNAc structures on several glycoproteins and glycosphingolipids
Biochem. Biophys. Res. Commun.
354
522-527
2007
Drosophila melanogaster, Drosophila sp. (in: flies)
Manually annotated by BRENDA team
Haines, N.; Stewart, B.A.
Functional roles for beta1,4-N-acetylgalactosaminyltransferase-A in Drosophila larval neurons and muscles
Genetics
175
671-679
2007
Drosophila sp. (in: flies)
Manually annotated by BRENDA team
Malagolini, N.; Santini, D.; Chiricolo, M.; DallOlio, F.
Biosynthesis and expression of the Sda and sialyl Lewis x antigens in normal and cancer colon
Glycobiology
17
688-697
2007
Homo sapiens
Manually annotated by BRENDA team
Huang, J.; Liang, J.T.; Huang, H.C.; Shen, T.L.; Chen, H.Y.; Lin, N.Y.; Che, M.I.; Lin, W.C.; Huang, M.C.
Beta1,4-N-acetylgalactosaminyltransferase III enhances malignant phenotypes of colon cancer cells
Mol. Cancer Res.
5
543-552
2007
Homo sapiens
Manually annotated by BRENDA team
Johswich, A.; Kraft, B.; Wuhrer, M.; Berger, M.; Deelder, A.M.; Hokke, C.H.; Gerardy-Schahn, R.; Bakker, H.
Golgi targeting of Drosophila melanogaster beta4GalNAcTB requires a DHHC protein family-related protein as a pilot
J. Cell Biol.
184
173-183
2009
Drosophila melanogaster
Manually annotated by BRENDA team
Fiete, D.; Beranek, M.; Baenziger, J.U.
Peptide-specific transfer of N-acetylgalactosamine to O-linked glycans by the glycosyltransferases beta1,4-N-acetylgalactosaminyl transferase 3 (beta4GalNAc-T3) and beta4GalNAc-T4
J. Biol. Chem.
287
29204-29212
2012
Homo sapiens (Q76KP1)
Manually annotated by BRENDA team
Che, M.I.; Huang, J.; Hung, J.S.; Lin, Y.C.; Huang, M.J.; Lai, H.S.; Hsu, W.M.; Liang, J.T.; Huang, M.C.
beta1,4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells
Oncotarget
5
3673-3684
2014
Homo sapiens (Q6L9W6), Homo sapiens
Manually annotated by BRENDA team