2.4.1.245: alpha,alpha-trehalose synthase

This is an abbreviated version!
For detailed information about alpha,alpha-trehalose synthase, go to the full flat file.

Reaction

Synonyms

PH1035, TaTS, TmTreT, trehalose glycosyltransferring synthase, Trehalose synthase, TreT

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.245 alpha,alpha-trehalose synthase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
320	AA Sequence
7	Application
1	CAS Registry Number
7	Cloned(Commentary)
1	Crystallization (Commentary)
1	General Information
9	Inhibitors
13	kcat/KM [mM/s]
24	KM Value [mM]
13	Metals/Ions
10	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
23	Organism
5	Pathway
7	pH Optimum
2	pH Range
2	pH Stability
14	Protein Variants
3	Purification (Commentary)
2	Reaction
1	Reaction Type
14	Reference
48	Substrates and Products (Substrate)
4	Subunits
16	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
3	Temperature Range [°C]
4	Temperature Stability [°C]
13	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 2.4.1.245 - alpha,alpha-trehalose synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Systematic Name Search

NDP-alpha-D-glucose:D-glucose 1-alpha-D-glucosyltransferase

Requires Mg2+ for maximal activity [1]. The enzyme-catalysed reaction is reversible [1]. In the reverse direction to that shown above, the enzyme is specific for alpha,alpha-trehalose as substrate, as it cannot use alpha- or beta-paranitrophenyl glucosides, maltose, sucrose, lactose or cellobiose [1]. While the enzymes from the thermophilic bacterium Rubrobacter xylanophilus and the hyperthermophilic archaeon Pyrococcus horikoshii can use ADP-, UDP- and GDP-alpha-D-glucose to the same extent [2,3], that from the hyperthermophilic archaeon Thermococcus litoralis has a marked preference for ADP-alpha-D-glucose [1] and that from the hyperthermophilic archaeon Thermoproteus tenax has a marked preference for UDP-alpha-D-glucose [4].