2.4.1.246: mannosylfructose-phosphate synthase

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For detailed information about mannosylfructose-phosphate synthase, go to the full flat file.

Reaction

Synonyms

MFPS

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.246 mannosylfructose-phosphate synthase

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705	AA Sequence
1	CAS Registry Number
2	Organism
1	Pathway
1	Reaction
2	Reference
2	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.4.1.246 - mannosylfructose-phosphate synthase

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SYSTEMATIC NAME

IUBMB Comments

GDP-mannose:D-fructose-6-phosphate 2-alpha-D-mannosyltransferase

This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg2+ or Mn2+ for activity. GDP-mannose can be replaced by ADP-mannose but with a concomitant decrease in activity. The product of this reaction is dephosphorylated by EC 3.1.3.79 (mannosylfructose-phosphate phosphatase) to form the non-reducing disaccharide mannosylfructose, which is the major endogenous osmolyte produced by several alpha-proteobacteria in response to osmotic stress. The F in the product name is used to indicate that the fructose residue of sucrose carries the substituent.