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2.4.1.259: dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase

This is an abbreviated version!
For detailed information about dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase, go to the full flat file.

Reaction

dolichyl beta-D-mannosyl phosphate
+
alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol
=
alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol
+
dolichyl phosphate

Synonyms

ALG9, ALG9 alpha1,2 mannosyltransferase, ALG9 mannosyltransferase, dolichylphosphomannose-dependent ALG9 mannosyltransferase, EBS3, EC 2.4.1.130

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.259 dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase

Expression

Expression on EC 2.4.1.259 - dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
expression of ALG9 is increased by 4.3fold in Galactosaemia versus healthy controls
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