2.4.1.274: glucosylceramide beta-1,4-galactosyltransferase

This is an abbreviated version!
For detailed information about glucosylceramide beta-1,4-galactosyltransferase, go to the full flat file.

Reaction

Synonyms

B4GalT5, B4GalT6, beta-1,4-galactosyltransferase V, beta-1,4-GalT-V, beta4-galactosyltransferase 5, beta4GalT5, Lac-Cer synthase, LacCer synthase, lactosylceramide synthase, UDP-Ga1:glucosylceramide beta1->4galactosyltransferase, UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase, UDP-galactose:GlcCer, beta1-4 galactosyltransferase, UDPgalactose:glucosylceramide beta1->4-galactosyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.274 glucosylceramide beta-1,4-galactosyltransferase

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Results	in table
2	Activating Compound
13	AA Sequence
3	Application
3	Cloned(Commentary)
46	Disease/ Diagnostics
3	Expression
4	General Information
6	KM Value [mM]
2	Localization
6	Metals/Ions
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
13	Organism
6	Pathway
4	pH Optimum
1	pI Value
1	Posttranslational Modification
2	Purification (Commentary)
1	Reaction
11	Reference
34	Source Tissue
1	Specific Activity [micromol/min/mg]
10	Substrates and Products (Substrate)
2	Subunits
21	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 2.4.1.274 - glucosylceramide beta-1,4-galactosyltransferase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

UDP-alpha-D-galactose + glucosylceramide

UDP + lactosylceramide

Mus musculus

Q9JMK0

-

736198

-

-

?

UDP-galactose + beta-D-glucosyl-(1<->1)-ceramide

UDP + beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

2 entries

UDP-galactose + beta-D-glucosyl-(1<->1)-ceramide

UDP + beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Homo sapiens

-

the enzyme is involved in the synthesis of several different major classes of glycosphingolipids

714364

-

-

?

UDP-galactose + beta-D-glucosyl-(1<->1)-ceramide

UDP + beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Rattus norvegicus

-

-

714128, 715435

-

-

?