2.4.1.278: 3-alpha-mycarosylerythronolide B desosaminyl transferase

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For detailed information about 3-alpha-mycarosylerythronolide B desosaminyl transferase, go to the full flat file.

DesVII, EryCIII, glycosyltransferase EryCIII

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Results	in table
97	AA Sequence
2	Application
2	Cloned(Commentary)
2	Cofactor
2	General Information
1	kcat/KM [mM/s]
1	KM Value [mM]
1	Natural Substrates/ Products (Substrates)
3	Organism
6	Pathway
1	pH Optimum
2	Purification (Commentary)
1	Reaction
3	Reference
1	Storage Stability
5	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Turnover Number [1/s]

Substrates Products on EC 2.4.1.278 - 3-alpha-mycarosylerythronolide B desosaminyl transferase

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dTDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 3-alpha-mycarosylerythronolide B

dTDP + erythromycin D

dTDP-D-desosamine + 3-alpha-L-mycarosylerythronolide B

dTDP + erythromycin D

dTDP-D-mycaminose + 3-alpha-mycarosylerythronolide B

dTDP + erythromycin M

the activated enzyme is capable of transferring an alternative sugar donor

additional information

no activity with: TDP-D-mycaminose, 6-deoxy-erythronolide B, 10-deoxymethynolide