2.4.1.288: galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase
This is an abbreviated version!
For detailed information about galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.288
-
2.4.1.288
-
galactan
-
mycobacterial
-
tuberculosis
-
galf
-
polysaccharide
-
udp-galf
-
udp-galactofuranose
-
glycosyltransferases
-
arabinogalactan
-
glycoconjugate
-
mycolic
-
trisaccharide
-
tetrasaccharide
-
mycolyl-arabinogalactan-peptidoglycan
-
galactosyltransferase
-
polymerizing
-
l-arabinofuranose
-
galactomannans
-
anti-tuberculosis
-
fungal-type
- 2.4.1.288
- galactan
-
mycobacterial
- tuberculosis
-
galf
- polysaccharide
-
udp-galf
- udp-galactofuranose
- glycosyltransferases
- arabinogalactan
- glycoconjugate
-
mycolic
- trisaccharide
- tetrasaccharide
-
mycolyl-arabinogalactan-peptidoglycan
-
galactosyltransferase
-
polymerizing
- l-arabinofuranose
- galactomannans
-
anti-tuberculosis
-
fungal-type
Reaction
28 UDP-alpha-D-galactofuranose
+
Synonyms
galactofuranosyl transferase 2, galactofuranosyltransferase, galactosyl transferase, GalTr, GlfT, GlfT2, LmjF.25.0010, LMJF_25_0010, LPG1, LPG1G, LPG1G2, LPG1L, Rv3808c
ECTree
2.4.1.288 galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.4.1.288 - galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
dTDP-alpha-D-galactofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
GDP-alpha-D-glucopyranose + methyl alpha-D-mannopyrannoside
UDP + ?
-
-
-
?
GDP-alpha-D-mannopyranose + methyl alpha-D-mannopyrannoside
UDP + ?
-
-
-
?
UDP-2''-O-methyl-alpha-D-galactofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-3''-deoxy-alpha-D-xylo-hexofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-3-deoxy-alpha-D-threo-hexofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-5''-O-methyl-alpha-D-galactofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-5-deoxy-alpha-D-galactofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-5-deoxy-alpha-D-galactofuranose + beta-Galf-(1->6)-beta-Galf-(1->5)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-6''-O-methyl-alpha-D-galactofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-6-deoxy-alpha-D-galactofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-6-deoxy-alpha-D-galactofuranose + beta-Galf-(1->6)-beta-Galf-(1->5)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-alpha-D-arabinofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-alpha-D-arabinofuranose + beta-Galf-(1->6)-beta-Galf-(1->5)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-alpha-D-galactofuranose + 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
UDP-alpha-D-galactofuranose + 19-phenoxy-nondec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
UDP-alpha-D-galactofuranose + 9-phenoxy-non-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP-alpha-D-galactofuranose + beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-beta-D-Galf-O(CH2)7CH3
beta-D-Galf-(1->6)-beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-beta-D-Galf-O(CH2)7CH3
-
-
-
-
?
UDP-alpha-D-galactofuranose + beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-beta-D-Galf-O(CH2)7CH3
UDP + ?
UDP-alpha-D-galactofuranose + beta-D-Galf-(1->6)-beta-D-Galf-(1->5)-beta-D-Galf-O(CH2)7CH3
?
-
-
-
-
?
UDP-alpha-D-galactofuranose + beta-D-Galf-(1->6)-beta-D-Galf-(1->5)-beta-D-Galf-O(CH2)7CH3
UDP + beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-beta-D-Galf-(1->5)-beta-D-Galf-O(CH2)7CH3
-
-
-
-
?
UDP-alpha-D-galactofuranose + beta-Galf-(1->5)-beta-Galf-(1->6)-beta-Galf-octyl
UDP + ?
-
best donor-acceptor combination, dual recognition of both the terminal C-5 and C-6 hydroxyl groups of the acceptor substrate are required for GlfT2 activity
-
-
?
UDP-alpha-D-galactofuranose + beta-Galf-(1->6)-beta-Galf-(1->5)-beta-Galf-octyl
UDP + ?
-
-
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranose
nonnatural substrate
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranose
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
natural substrate
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
nonnatural substrate
-
-
?
UDP-alpha-D-galactofuranose + dec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
-
-
-
-
?
UDP-alpha-D-galactofuranose + methyl alpha-D-mannopyrannoside
UDP + ?
-
-
-
?
UDP-alpha-D-galactofuranose + octyl beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-2-acetamido-2-deoxy-alpha-D-glucopyranoside
UDP + octyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-2-acetamido-2-deoxy-alpha-D-glucopyranoside
-
-
-
-
?
UDP-alpha-D-galactopyranose + methyl alpha-D-mannopyrannoside
UDP + ?
-
-
-
?
UDP-alpha-D-glucopyranose + methyl alpha-D-mannopyrannoside
UDP + ?
-
-
-
?
UDP-alpha-D-arabinofuranose + octyl beta-Galf-(1->6)-beta-Galf-(1->5)-beta-Galf
?
-
-
-
?
UDP-alpha-D-arabinofuranose + octyl beta-Galf-(1->6)-beta-Galf-(1->5)-beta-Galf
?
-
-
-
?
UDP-alpha-D-galactofuranose + 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
-
the enzyme functions as a processive polymerase only with 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
-
?
UDP-alpha-D-galactofuranose + 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
-
the enzyme functions as a processive polymerase only with 12-phenoxy-dodec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
-
?
UDP-alpha-D-galactofuranose + 19-phenoxy-nondec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
-
-
-
-
?
UDP-alpha-D-galactofuranose + 19-phenoxy-nondec-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
-
-
-
-
?
UDP-alpha-D-galactofuranose + 9-phenoxy-non-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
-
-
-
-
?
UDP-alpha-D-galactofuranose + 9-phenoxy-non-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
UDP + ?
-
-
-
-
?
UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
-
-
-
?
UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
the beta-(1->5)-transferase activity of the enzyme first glycosylates the galactofuranosyl residue at the nonreducing terminus of the polyprenol-bound tetrasaccharide acceptor. The resulting product is then a substrate for the beta-(1->6)-transferase activity of the enzyme
-
-
?
UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
the enzyme adds the third and subsequent alpha-D-galactofuranosyl residues to the growing galactan chain
-
-
?
UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
-
-
-
?
UDP-alpha-D-galactofuranose + beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
UDP + [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol
-
-
-
-
?
UDP-alpha-D-galactofuranose + beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-beta-D-Galf-O(CH2)7CH3
UDP + ?
-
-
-
-
?
UDP-alpha-D-galactofuranose + beta-D-Galf-(1->5)-beta-D-Galf-(1->6)-beta-D-Galf-O(CH2)7CH3
UDP + ?
-
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
-
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
natural substrate
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
-
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
natural substrate
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
-
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->6)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranose
-
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranose
-
-
-
?
UDP-alpha-D-galactofuranose + D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranose
UDP + D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranose
natural substrate
-
-
?
additional information
?
-
among hexoses, monosaccharides, 4-nitrophenyl-furanoses, 4-nitorphenyl-hexoses and disaccharides tested, only methyl alpha-D-mannopyrannoside efficiently reacts as an acceptor. No donor: UDP-alpha-D-glucuronic acid
-
-
-
additional information
?
-
among hexoses, monosaccharides, 4-nitrophenyl-furanoses, 4-nitorphenyl-hexoses and disaccharides tested, only methyl alpha-D-mannopyrannoside efficiently reacts as an acceptor. No donor: UDP-alpha-D-glucuronic acid
-
-
-
additional information
?
-
among hexoses, monosaccharides, 4-nitrophenyl-furanoses, 4-nitorphenyl-hexoses and disaccharides tested, only methyl alpha-D-mannopyrannoside efficiently reacts as an acceptor. No donor: UDP-alpha-D-glucuronic acid
-
-
-
additional information
?
-
-
among hexoses, monosaccharides, 4-nitrophenyl-furanoses, 4-nitorphenyl-hexoses and disaccharides tested, only methyl alpha-D-mannopyrannoside efficiently reacts as an acceptor. No donor: UDP-alpha-D-glucuronic acid
-
-
-
additional information
?
-
among hexoses, monosaccharides, 4-nitrophenyl-furanoses, 4-nitorphenyl-hexoses and disaccharides tested, only methyl alpha-D-mannopyrannoside efficiently reacts as an acceptor. No donors: UDP-alpha-D-glucopyranose, UDP-alpha-D-glucuronic acid, GDP-alpha-D-glucopyranose, GDP-alpha-D-mannopyranose
-
-
-
additional information
?
-
among hexoses, monosaccharides, 4-nitrophenyl-furanoses, 4-nitorphenyl-hexoses and disaccharides tested, only methyl alpha-D-mannopyrannoside efficiently reacts as an acceptor. No donors: UDP-alpha-D-glucopyranose, UDP-alpha-D-glucuronic acid, GDP-alpha-D-glucopyranose, GDP-alpha-D-mannopyranose
-
-
-
additional information
?
-
among hexoses, monosaccharides, 4-nitrophenyl-furanoses, 4-nitorphenyl-hexoses and disaccharides tested, only methyl alpha-D-mannopyrannoside efficiently reacts as an acceptor. No donors: UDP-alpha-D-glucopyranose, UDP-alpha-D-glucuronic acid, GDP-alpha-D-glucopyranose, GDP-alpha-D-mannopyranose
-
-
-
additional information
?
-
-
among hexoses, monosaccharides, 4-nitrophenyl-furanoses, 4-nitorphenyl-hexoses and disaccharides tested, only methyl alpha-D-mannopyrannoside efficiently reacts as an acceptor. No donors: UDP-alpha-D-glucopyranose, UDP-alpha-D-glucuronic acid, GDP-alpha-D-glucopyranose, GDP-alpha-D-mannopyranose
-
-
-
additional information
?
-
-
GlfT2 has one active site pocket capable of catalyzing both beta-(1->5) and beta-(1->6) galactofuranosyl transfer reactions
-
-
?
additional information
?
-
-
GlfT2 mediates synthesis of the galactan polymer, which contains between 20 and 40 D-galactofuranose residues connected by alternating beta-D-galactofuranosyl-(1->5)-D-galactofuranose and beta-D-galactofuranosyl-(1->6)-D-galactofuranose linkages. Elongation occurs by addition of D-galactofuranose residues from UDP-alpha-D-galactofuranose to the nonreducing end of a lipid-linked acceptor
-
-
?
additional information
?
-
-
no activity with 4-phenoxy-but-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
-
?
additional information
?
-
GlfT2 is promiscuous in its substrate preferences. It preferentially acts on substrates in which the lipid-bearing Gal residue is connected to the sequence by a (1->)-beta-glycosidic linkage. The preferential formation of alternating (1->6)-beta-Galf and (1->5)-beta-Galf residues arises not from substrate binding but during catalytic processive polymerization
-
-
-
additional information
?
-
-
GlfT2 is promiscuous in its substrate preferences. It preferentially acts on substrates in which the lipid-bearing Gal residue is connected to the sequence by a (1->)-beta-glycosidic linkage. The preferential formation of alternating (1->6)-beta-Galf and (1->5)-beta-Galf residues arises not from substrate binding but during catalytic processive polymerization
-
-
-
additional information
?
-
GlfT2 is promiscuous in its substrate preferences. It preferentially acts on substrates in which the lipid-bearing Gal residue is connected to the sequence by a (1->6)-beta-glycosidic linkage. The preferential formation of alternating (1->6)-beta-Galf and (1->5)-beta-Galf residues arises not from substrate binding but during catalytic processive polymerization
-
-
-
additional information
?
-
-
GlfT2 is promiscuous in its substrate preferences. It preferentially acts on substrates in which the lipid-bearing Gal residue is connected to the sequence by a (1->6)-beta-glycosidic linkage. The preferential formation of alternating (1->6)-beta-Galf and (1->5)-beta-Galf residues arises not from substrate binding but during catalytic processive polymerization
-
-
-
additional information
?
-
GlfT2 is promiscuous in its substrate preferences. It preferentially acts on substrates in which the lipid-bearing Gal residue is connected to the sequence by a (1->)-beta-glycosidic linkage. The preferential formation of alternating (1->6)-beta-Galf and (1->5)-beta-Galf residues arises not from substrate binding but during catalytic processive polymerization
-
-
-
additional information
?
-
GlfT2 is promiscuous in its substrate preferences. It preferentially acts on substrates in which the lipid-bearing Gal residue is connected to the sequence by a (1->6)-beta-glycosidic linkage. The preferential formation of alternating (1->6)-beta-Galf and (1->5)-beta-Galf residues arises not from substrate binding but during catalytic processive polymerization
-
-
-
additional information
?
-
-
GlfT2 mediates synthesis of the galactan polymer, which contains between 20 and 40 D-galactofuranose residues connected by alternating beta-D-galactofuranosyl-(1->5)-D-galactofuranose and beta-D-galactofuranosyl-(1->6)-D-galactofuranose linkages. Elongation occurs by addition of D-galactofuranose residues from UDP-alpha-D-galactofuranose to the nonreducing end of a lipid-linked acceptor
-
-
?
additional information
?
-
-
no activity with 4-phenoxy-but-2-enyl beta-D-galactofuranosyl-(1->6)-beta-D-galactofuranoside
-
-
?
additional information
?
-
-
octyl alpha-L-rhamnopyranosyl-(1->3)-2-acetamido-2-deoxy-alpha-D-glucopyranoside and octyl alpha-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-2-acetamido-2-deoxy-alpha-D-glucopyranoside are no effective substrates
-
-
?
