2.4.1.302: L-demethylnoviosyl transferase

This is an abbreviated version!
For detailed information about L-demethylnoviosyl transferase, go to the full flat file.

Reaction

Synonyms

NovM

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.302 L-demethylnoviosyl transferase

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Results	in table
65	AA Sequence
1	Cloned(Commentary)
1	General Information
2	Inhibitors
7	kcat/KM [mM/s]
1	Ki Value [mM]
5	KM Value [mM]
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
3	Organism
5	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
3	Reference
13	Substrates and Products (Substrate)
1	Subunits
3	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
5	Turnover Number [1/s]

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Reference on EC 2.4.1.302 - L-demethylnoviosyl transferase

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721589

Freel Meyers, C.L.; Oberth�r, M.; Anderson, J.W.; Kahne, D.; Walsh, C.T.

Initial characterization of novobiocic acid noviosyl transferase activity of NovM in biosynthesis of the antibiotic novobiocin

Biochemistry

4179-4189

2003

Streptomyces niveus

12680772

723329

Albermann, C.; Soriano, A.; Jiang, J.; Vollmer, H.; Biggins, J.B.; Barton, W.A.; Lesniak, J.; Nikolov, D.B.; Thorson, J.S.

Substrate specificity of NovM: implications for novobiocin biosynthesis and glycorandomization

Org. Lett.

933-936

2003

Streptomyces niveus

12633109

723619

Pi, N.; Meyers, C.L.; Pacholec, M.; Walsh, C.T.; Leary, J.A.

Mass spectrometric characterization of a three-enzyme tandem reaction for assembly and modification of the novobiocin skeleton

Proc. Natl. Acad. Sci. USA

101

10036-10041

2004

Streptomyces sp.

15218104