2.4.1.306: UDP-GalNAc:alpha-D-GalNAc-diphosphoundecaprenol alpha-1,3-N-acetylgalactosaminyltransferase
This is an abbreviated version!
For detailed information about UDP-GalNAc:alpha-D-GalNAc-diphosphoundecaprenol alpha-1,3-N-acetylgalactosaminyltransferase, go to the full flat file.
Reaction
Synonyms
WbnH
ECTree
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Substrates Products
Substrates Products on EC 2.4.1.306 - UDP-GalNAc:alpha-D-GalNAc-diphosphoundecaprenol alpha-1,3-N-acetylgalactosaminyltransferase
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REACTION DIAGRAM
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-(CH2)10-CH3
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-(CH2)10-CH3
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-11-phenoxyundecanol
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-11-phenoxyundecanol
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-(CH2)10-CH3
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95% of the activity with UDP-N-acetyl-D-galactosamine + D-GalNAc-alpha-diphospho-11-phenoxyundecanol
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-
?
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-(CH2)10-CH3
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-(CH2)10-CH3
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95% of the activity with UDP-N-acetyl-D-galactosamine + D-GalNAc-alpha-diphospho-11-phenoxyundecanol
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-
?
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-11-phenoxyundecanol
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synthetic acceptor substrate. Diphosphate and hydrophobic lipid moiety are structural requirements for WbnH activity
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-
?
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-11-phenoxyundecanol
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-11-phenoxyundecanol
-
synthetic acceptor substrate. Diphosphate and hydrophobic lipid moiety are structural requirements for WbnH activity
-
-
?
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
Q5J7D6
biosynthesis of the O-polysaccharide is initiated with sequential assembly of repeating units on the cytoplasmic face of the inner membrane by glycosyltransferases WbnH, WbnJ, WbnK and WbnI
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-
?
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
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the enzyme is involved in the O-repeating unit biosynthesis, the first committed step in lipopolysaccharide biosynthesis in a variety of gram-negative bacteria
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-
?
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
-
the enzyme is involved in the O-repeating unit biosynthesis, the first committed step in lipopolysaccharide biosynthesis in a variety of gram-negative bacteria
-
-
?
UDP-N-acetyl-alpha-D-galactosamine + N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
Q5J7D6
biosynthesis of the O-polysaccharide is initiated with sequential assembly of repeating units on the cytoplasmic face of the inner membrane by glycosyltransferases WbnH, WbnJ, WbnK and WbnI
-
-
?
?
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the natural substrate N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol is difficult to isolate from natural bacterial sources due to the low abundance. The highly hydrophobic feature of the 55-carbon undecaprenyl chain makes it hard to handle
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-
?
additional information
?
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the natural substrate N-acetyl-alpha-D-galactosaminyl-diphospho-ditrans,octacis-undecaprenol is difficult to isolate from natural bacterial sources due to the low abundance. The highly hydrophobic feature of the 55-carbon undecaprenyl chain makes it hard to handle
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-
?