2.4.1.308: GDP-Fuc:beta-D-Gal-1,3-alpha-D-GalNAc-1,3-alpha-GalNAc-diphosphoundecaprenol alpha-1,2-fucosyltransferase
This is an abbreviated version!
For detailed information about GDP-Fuc:beta-D-Gal-1,3-alpha-D-GalNAc-1,3-alpha-GalNAc-diphosphoundecaprenol alpha-1,2-fucosyltransferase, go to the full flat file.
Reaction
Synonyms
WbnK
ECTree
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Substrates Products
Substrates Products on EC 2.4.1.308 - GDP-Fuc:beta-D-Gal-1,3-alpha-D-GalNAc-1,3-alpha-GalNAc-diphosphoundecaprenol alpha-1,2-fucosyltransferase
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REACTION DIAGRAM
GDP-beta-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
GDP-beta-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-OMe
GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-OMe
GDP-beta-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
biosynthesis of the O-polysaccharide is initiated with sequential assembly of repeating units on the cytoplasmic face of the inner membrane by glycosyltransferases WbnH, WbnJ, WbnK and WbnI. The enzyme is involved in the the biosynthesis of the O-polysaccharide repeating unit of Escherichia coli serotype O86
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GDP-beta-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-diphospho-ditrans,octacis-undecaprenol
biosynthesis of the O-polysaccharide is initiated with sequential assembly of repeating units on the cytoplasmic face of the inner membrane by glycosyltransferases WbnH, WbnJ, WbnK and WbnI. The enzyme is involved in the the biosynthesis of the O-polysaccharide repeating unit of Escherichia coli serotype O86
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GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-OMe
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GDP-beta-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-OMe
GDP + alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-OMe
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15% of the activity compared to beta-Gal-(1->3)-alpha-GalNAc-OMe
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GDP-beta-L-fucose + beta-D-Gal-OMe
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15% of the activity compared to beta-Gal-(1->3)-alpha-GalNAc-OMe
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WbnK requires a terminal beta-1,3-linked Gal sugar sequence as acceptor
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additional information
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WbnK requires a terminal beta-1,3-linked Gal sugar sequence as acceptor
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