2.4.1.322: devancosaminyl-vancomycin vancosaminetransferase

This is an abbreviated version!
For detailed information about devancosaminyl-vancomycin vancosaminetransferase, go to the full flat file.

Reaction

Synonyms

desvancosamine-vancomycin TDP-vancosaminyltransferase, GtfD, L-vancosaminyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.322 devancosaminyl-vancomycin vancosaminetransferase

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Results	in table
5	AA Sequence
2	Application
3	Cloned(Commentary)
1	Crystallization (Commentary)
4	kcat/KM [mM/s]
5	KM Value [mM]
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
6	Organism
1	Pathway
1	pH Optimum
2	Protein Variants
1	Purification (Commentary)
1	Reaction
6	Reference
20	Substrates and Products (Substrate)
2	Subunits
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
6	Turnover Number [1/s]

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Reference on EC 2.4.1.322 - devancosaminyl-vancomycin vancosaminetransferase

Please use the Reference Search for a specific query.

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721585

Losey, H.C.; Peczuh, M.W.; Chen, Z.; Eggert, U.S.; Dong, S.D.; Pelczer, I.; Kahne, D.; Walsh, C.T.

Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: novel glycopeptides

Biochemistry

4745-4755

2001

Amycolatopsis orientalis (Q9AFC7)

11294642

724268

Mulichak, A.M.; Lu, W.; Losey, H.C.; Walsh, C.T.; Garavito, R.M.

Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands

Biochemistry

5170-5180

2004

Amycolatopsis orientalis (Q9AFC7)

15122882

727292

Losey, H.C.; Jiang, J.; Biggins, J.B.; Oberthuer, M.; Ye, X.Y.; Dong, S.D.; Kahne, D.; Thorson, J.S.; Walsh, C.T.

Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides

Chem. Biol.

1305-1314

2002

Amycolatopsis orientalis (Q9AFC7)

12498883

727659

Oberthuer, M.; Leimkuhler, C.; Kruger, R.G.; Lu, W.; Walsh, C.T.; Kahne, D.

A systematic investigation of the synthetic utility of glycopeptide glycosyltransferases

J. Am. Chem. Soc.

127

10747-10752

2005

Amycolatopsis orientalis (Q9AFC7)

16045364

736938

Nakayama, A.; Okano, A.; Feng, Y.; Collins, J.C.; Collins, K.C.; Walsh, C.T.; Boger, D.L.

Enzymatic glycosylation of vancomycin aglycon: completion of a total synthesis of vancomycin and N- and C-terminus substituent effects of the aglycon substrate

Org. Lett.

3572-3575

2014

Amycolatopsis orientalis (Q9AFC7), Amycolatopsis orientalis ATCC 19795 (Q9AFC7)

24954524