2.4.1.331: 8-demethyltetracenomycin C L-rhamnosyltransferase
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For detailed information about 8-demethyltetracenomycin C L-rhamnosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.331
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2.4.1.331
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tetracenomycins
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aglycone
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deoxysugars
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lividans
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olivaceus
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synthesis
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oleandomycin
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polyketide
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glycosyltransferases
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4-ketoreductase
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medicine
- 2.4.1.331
-
tetracenomycins
-
aglycone
-
deoxysugars
- lividans
- olivaceus
- synthesis
- oleandomycin
- polyketide
- glycosyltransferases
- 4-ketoreductase
- medicine
Reaction
Synonyms
elloramycin glycosyltransferase, ElmGT
ECTree
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Application
Application on EC 2.4.1.331 - 8-demethyltetracenomycin C L-rhamnosyltransferase
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medicine
synthesis
generation of L- and D-stereoisomers of amicetose by combining sugar biosynthesis genes from four different antibiotic gene clusters and transfer of both sugars to the elloramycin aglycone by the sugar flexible ElmGT glycosyltransferase to yield antitumor tetracenomycins
medicine
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generation of L- and D-stereoisomers of amicetose by combining sugar biosynthesis genes from four different antibiotic gene clusters and transfer of both sugars to the elloramycin aglycone by the sugar flexible ElmGT glycosyltransferase to yield antitumor tetracenomycins
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expression of NDP-glucose-synthase OleS, NDP-glucose-4, 6-dehydratase OleE, 2, 3-dehydratase OleV, 3, 5-epimerase OleL and 3-ketoreductase OleW in combination with elloramycin glycosyltransferase ElmGt in Streptomyces lividans results in accumulation of 8-demthyltetracenomycin C plus 8-demethyl-8-(4-dehydro)-alpha-L-olivosyl-tetracenomycin and 8-demethyl-8-alpha-L-olivosyl-tetracenomycin
synthesis
generation of L- and D-stereoisomers of amicetose by combining sugar biosynthesis genes from four different antibiotic gene clusters and transfer of both sugars to the elloramycin aglycone by the sugar flexible ElmGT glycosyltransferase to yield antitumor tetracenomycins
synthesis
-
expression of NDP-glucose-synthase OleS, NDP-glucose-4, 6-dehydratase OleE, 2, 3-dehydratase OleV, 3, 5-epimerase OleL and 3-ketoreductase OleW in combination with elloramycin glycosyltransferase ElmGt in Streptomyces lividans results in accumulation of 8-demthyltetracenomycin C plus 8-demethyl-8-(4-dehydro)-alpha-L-olivosyl-tetracenomycin and 8-demethyl-8-alpha-L-olivosyl-tetracenomycin
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synthesis
-
generation of L- and D-stereoisomers of amicetose by combining sugar biosynthesis genes from four different antibiotic gene clusters and transfer of both sugars to the elloramycin aglycone by the sugar flexible ElmGT glycosyltransferase to yield antitumor tetracenomycins
-