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2.4.1.54: undecaprenyl-phosphate mannosyltransferase

This is an abbreviated version!
For detailed information about undecaprenyl-phosphate mannosyltransferase, go to the full flat file.

Word Map on EC 2.4.1.54

Reaction

GDP-alpha-D-mannose
+
undecaprenyl phosphate
=
GDP
+
D-mannosyl-1-phosphoundecaprenol

Synonyms

GDP mannose-undecaprenyl phosphate mannosyltransferase, GDP-D-mannose:lipid phosphate transmannosylase, guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase, mannosyl-1-phosphoryl-undecaprenol synthetase, mannosylphosphorylundecaprenol synthase, mannosyltransferase, guanosine diphosphomannose-undecaprenyl phosphate, MPU synthetase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.54 undecaprenyl-phosphate mannosyltransferase

Substrates Products

Substrates Products on EC 2.4.1.54 - undecaprenyl-phosphate mannosyltransferase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
GDPmannose + citronellyl phosphate
GDP + mannosyl-phosphorylcitronellol
show the reaction diagram
-
-
beta-isomer as product
?
GDPmannose + dolichyl phosphate
GDP + mannosyl-phosphoryldolichol
show the reaction diagram
-
-
beta-isomer as product
?
GDPmannose + ficaprenyl phosphate
GDP + mannosyl-1-phosphorylficaprenol
show the reaction diagram
GDPmannose + phospholipid
GDP + mannosyl-1-phospholipid
show the reaction diagram
-
polyprenol type, involved in glycophospholipid biosynthesis
-
-
?
GDPmannose + phytanol phosphate
GDP + D-mannosyl-1-phosphophytanol
show the reaction diagram
-
reaction is reversed by GDP, but not by GMP, enzyme is relatively specific for GDPmannose, phytanol phosphate is a poorer glycosyl acceptor than the unidentified endogenous lipid phosphate substrate
-
-
r
GDPmannose + phytol phosphate
GDP + D-mannosyl-1-phosphophytol
show the reaction diagram
-
poor substrate
-
-
r
GDPmannose + polyisoprenyl phosphate
GDP + mannosyl-phosphorylpolyisoprenol
show the reaction diagram
GDPmannose + undecaprenyl phosphate
GDP + D-mannosyl-1-phosphoundecaprenol
show the reaction diagram
UDPglucose + ficaprenyl phosphate
GDP + glucosyl-1-phosphorylficaprenol
show the reaction diagram
-
in the reverse reaction UMP is no substrate
-
-
r
additional information
?
-