2.4.1.66: procollagen glucosyltransferase
This is an abbreviated version!
For detailed information about procollagen glucosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.66
-
2.4.1.66
-
prolyl
-
gg
-
4-hydroxylase
-
galactosyltransferase
-
propeptide
-
soleus
-
aminoterminal
-
hyp
-
tibialis
-
4-hydroxyproline
-
chick-embryo
- 2.4.1.66
-
prolyl
- gg
-
4-hydroxylase
-
galactosyltransferase
- propeptide
- soleus
-
aminoterminal
- hyp
- tibialis
- 4-hydroxyproline
-
chick-embryo
Reaction
Synonyms
collagen glucosyltransferase, collagen hydroxylysyl glucosyltransferase, galactosylhydroxylysine glucosyltransferase, galactosylhydroxylysyl glucosyltransferase, GGT, glucosyltransferase, uridine diphosphoglucose-collagen, LH3, LH3/PLOD3, lysyl hydroxylase, lysyl hydroxylase 3, More, multifunctional procollagen lysine hydroxylase and glycosyltransferase, PLOD3, UDP-glucose-collagen glucosyltransferase, UDP-glucose:galactosylhydroxylysine-collagen glucosyltransferase, uridine diphosphoglucose-collagen glucosyltransferase
ECTree
Advanced search results
General Information
General Information on EC 2.4.1.66 - procollagen glucosyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
malfunction
metabolism
physiological function
-
disorders of LH3 with a unique phenotype causing severe morbidity as a result of feauters that overlap with collagen disorders
malfunction
-
an impairment of lysyl hydroxylase 3 function significantly affects type I collagen fibrillogenesis
malfunction
-
lysyl hydroxylase 3-mediated glucosylation occurs at specific sites in collagen, including cross-linking sites, and suppression of this modification results in defective collagen and mineralization
-
lysyl hydroxylase 3 functions as glucosyltransferase in type I collagen
metabolism
-
the enzyme is commonly involved in biosynthesis of collagenous proteins
-
forms part of the many posttranslational modifications required during collagen biosynthesis
physiological function
-
organization of the extracellular matrix and cytoskeleton
physiological function
organization of the extracellular matrix and cytoskeleton
physiological function
-
the lysyl hydroxylase 3-mediated glucosylation occurs at the specific molecular loci in the type I collagen molecule and plays critical roles in controlling collagen cross-linking, fibrillogenesis, and mineralization
physiological function
-
the major function of lysyl hydroxylase 3 in osteoblasts is to glucosylate galactosylhydroxylysine residues in type I collagen
physiological function
-
fibroblast cell surface recruitment of matrix metalloproteinase-9 via its fibronectin-like domain by lysyl hydroxylase 3 induces transforming growth factor-beta activation and myofibroblast differentiation