2.4.1.66: procollagen glucosyltransferase
This is an abbreviated version!
For detailed information about procollagen glucosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.66
-
2.4.1.66
-
prolyl
-
gg
-
4-hydroxylase
-
galactosyltransferase
-
propeptide
-
soleus
-
aminoterminal
-
hyp
-
tibialis
-
4-hydroxyproline
-
chick-embryo
- 2.4.1.66
-
prolyl
- gg
-
4-hydroxylase
-
galactosyltransferase
- propeptide
- soleus
-
aminoterminal
- hyp
- tibialis
- 4-hydroxyproline
-
chick-embryo
Reaction
Synonyms
collagen glucosyltransferase, collagen hydroxylysyl glucosyltransferase, galactosylhydroxylysine glucosyltransferase, galactosylhydroxylysyl glucosyltransferase, GGT, glucosyltransferase, uridine diphosphoglucose-collagen, LH3, LH3/PLOD3, lysyl hydroxylase, lysyl hydroxylase 3, More, multifunctional procollagen lysine hydroxylase and glycosyltransferase, PLOD3, UDP-glucose-collagen glucosyltransferase, UDP-glucose:galactosylhydroxylysine-collagen glucosyltransferase, uridine diphosphoglucose-collagen glucosyltransferase
ECTree
Advanced search results
Inhibitors
Inhibitors on EC 2.4.1.66 - procollagen glucosyltransferase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Fe3+
-
inhibits Mn2+-activated enzyme, 0.03 mM: 27% inhibition of activity with 0.01 mM Mn2+ and 0.035 mM UDP-glucose
Mn2+-UDP-complex
-
competitive inhibition to UDP-glucose, non-competitive to collagen
-
p-mercuribenzoate
-
0.0007 mM: 50% inhibition, substrates plus Mn2+ or Mn2+ alone partially protect
sucrose
-
membrane-bound enzyme, 0.42 M: 88% inhibition, also inhibits soluble enzyme
-
competitive to UDP-glucose; non-competitive to collagen; product inhibition
UDP
-
competitive to UDP-glucose; membrane-bound enzyme, 6 mM: complete inhibition; non-competitive to galactosylhydroxylysine; product inhibition
additional information
-
not inhibited by D-glucose, N-acetylglucosamine, N-acteylgalactosamine, Triton X-100, delta-hydroxylysine
-
additional information
-
membrane-bound enzyme: not inhibited by 100 mM D-glucosamine, 10 mM N-ethylmaleimide, 50 mM glucosylgalactosylhydroxylysine, soluble enzyme: not inhibited by 75 mM glucosylgalactosylhydroxylysine
-
additional information
-
total GGT activity decreases in vastus lateralis, rectus femoris and gastrocnemius muscles in streptozotocin-induced diabetic rats
-