2.4.1.80: ceramide glucosyltransferase

This is an abbreviated version!
For detailed information about ceramide glucosyltransferase, go to the full flat file.

Reaction

Synonyms

ceramide glucosyltransferase, ceramide glycosyltransferase, ceramide:UDP-glucose glucosyltransferase, ceramide:UDPGlc glucosyltransferase, cerebroside synthase, CGT, cgt-1, cgt-2, cgt-3, GCS, GCS1, GlcCer synthase, GlcCerS, GlcT, GlcT-1, glucosylceramide synthase, glucosyltransferase, uridine diphosphoglucose-ceramide, GluT, UDP glucose-ceramide glucosyltransferase, UDP-Glc:ceramide glucosyltransferase, UDP-glucoase:ceramide glucosyltransferase, UDP-glucose ceramide glucosyltransferase, UDP-glucose ceramide glycosyltransferase, UDP-glucose: ceramide glucosyltransferase, UDP-glucose:ceramide glucosyltransferase, Ugcg, uridine diphosphate (UDP)-glucose:N-acylsphingosine D-glucosyltransferase, uridine diphosphoglucose-ceramide glucosyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.80 ceramide glucosyltransferase

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Results	in table
24	Activating Compound
3411	AA Sequence
12	Application
1	CAS Registry Number
26	Cloned(Commentary)
64	Disease/ Diagnostics
11	Expression
18	General Information
5	General Stability
135	IC50 Value
208	Inhibitors
1	Ki Value [mM]
13	KM Value [mM]
37	Localization
27	Metals/Ions
27	Molecular Weight [Da]
58	Natural Substrates/ Products (Substrates)
419	Organism
7	Pathway
28	pH Optimum
1	pH Range
36	Protein Variants
9	Purification (Commentary)
4	Reaction
1	Reaction Type
90	Reference
2	Renatured (Commentary)
104	Source Tissue
30	Specific Activity [micromol/min/mg]
3	Storage Stability
152	Substrates and Products (Substrate)
8	Subunits
133	Synonyms
1	Systematic Name
25	Temperature Optimum [°C]
1	Temperature Range [°C]

Organism

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Organism on EC 2.4.1.80 - ceramide glucosyltransferase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Caenorhabditis elegans

8 entries

Candida albicans

-

489422

-

-

brenda

Canis lupus familiaris

2 entries

Cavia porcellus

-

489404

-

-

brenda

Chlorocebus aethiops

-

703917

-

-

brenda

Chlorocebus sabaeus

COS7 cells

703917

-

-

brenda

Cricetulus griseus

-

489424, 657538

-

-

brenda

Cryptococcus neoformans

-

681073

Q58FH5

SwissProt

brenda

Danio rerio

zebrafish

657538

-

-

brenda

Drosophila melanogaster

2 entries

Fusarium graminearum

-

694220

-

-

brenda

Gallus gallus

2 entries

Gossypium arboreum

-

658717

-

-

brenda

Homo sapiens

11 entries

Komagataella pastoris

-

489422

-

-

brenda

Mus musculus

5 entries

Mus musculus 129SvEv

-

736820

O88693

UniProt

brenda

Ovis aries

-

489404

-

-

brenda

Plasmodium falciparum

-

658636

-

-

brenda

Raphanus sativus

radish

489412

-

-

brenda

Rattus norvegicus

4 entries

Rattus norvegicus Sprague-Dawley

Sprague-Dawley

489405, 489421

-

-

brenda

Sus scrofa

-

489404, 489409, 489410, 489421

-

-

brenda

Caenorhabditis elegans

-

722356

-

-

brenda

Caenorhabditis elegans

isoform A; mutants without CGT

704785

Q21054

TREMBL

brenda

Caenorhabditis elegans

isoform B; mutants without CGT

704785

-

-

brenda

Caenorhabditis elegans

isoform c; mutants without CGT

704785

Q21054

TREMBL

brenda

Caenorhabditis elegans

isoform d; mutants without CGT

704785

-

-

brenda

Caenorhabditis elegans

mutants without CGT

704785

-

-

brenda

Caenorhabditis elegans

mutants without CGT

704785

O18037

TREMBL

brenda

Caenorhabditis elegans

several isoforms

489416, 489422

-

-

brenda

Canis lupus familiaris

-

703917

-

-

brenda

Canis lupus familiaris

MDCK cells

489420, 703917

-

-

brenda

Drosophila melanogaster

-

722902

-

-

brenda

Drosophila melanogaster

gene GlcT-1

659376

-

-

brenda

Gallus gallus

-

489421

-

-

brenda

Gallus gallus

13-14 days old embryo

489404

-

-

brenda

Homo sapiens

-

489404

-

-

brenda

Homo sapiens

-

489413, 489416

Q16739

SwissProt

brenda

Homo sapiens

-

489418

-

-

brenda

Homo sapiens

-

489419

Q16739

SwissProt

brenda

Homo sapiens

-

489420

-

-

brenda

Homo sapiens

-

489420

Q16739

SwissProt

brenda

Homo sapiens

-

489421

-

-

brenda

Homo sapiens

-

489421

Q16739

SwissProt

brenda

Homo sapiens

-

658310, 658382, 659915, 682888, 691551, 691791, 692543, 693944, 694529, 704444, 704776, 705012, 706417, 721726, 722787

-

-

brenda

Homo sapiens

-

730172, 735591, 735962, 736201, 736920, 756416

Q16739

SwissProt

brenda

Homo sapiens

gene GluT-1

489417

-

-

brenda

Mus musculus

-

489318, 489406, 489408, 489416, 489421, 679436, 680834, 681954, 682224, 682504

-

-

brenda

Mus musculus

-

703880

O88693

UniProt

brenda

Mus musculus

-

706417, 706799

-

-

brenda

Mus musculus

-

736820

O88693

UniProt

brenda

Mus musculus

hairless mice strain Cr1:SKH1-hr

489415

-

-

brenda

Rattus norvegicus

-

489404, 489407, 489414, 489416, 489418

-

-

brenda

Rattus norvegicus

-

489419, 489421, 489423

Q9R0E0

SwissProt

brenda

Rattus norvegicus

-

691551, 705907

-

-

brenda

Rattus norvegicus

Sprague-Dawley

489405, 489421

-

-

brenda