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2.4.1.88: globoside alpha-N-acetylgalactosaminyltransferase

This is an abbreviated version!
For detailed information about globoside alpha-N-acetylgalactosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.88

Reaction

UDP-N-acetyl-alpha-D-galactosamine
+
N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
=
UDP
 +
N-acetyl-alpha-D-galactosaminyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

Synonyms

acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-globoside alpha-, cis-AB-transferase, Forss-S, Forssman synthase, Forssman synthetase, Forssmann glycolipid synthetase, FS, GBGT1, globoside acetylgalactosaminyltransferase, globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, glycosyltransferase 6 (GT6) family member, GT6m5, GT6m6, GT6m7, histo-blood group ABO system transferase, More, uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.88 globoside alpha-N-acetylgalactosaminyltransferase

Activating Compound

Activating Compound on EC 2.4.1.88 - globoside alpha-N-acetylgalactosaminyltransferase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ATP
-
slightly activating
diphosphatidylglycerol
-
activation
GSH
-
slight stimulation
phosphatidic acid
-
activation
phosphatidylcholine
-
activation
phosphatidylethanolamine
-
activation
phosphatidylinositol
-
activation
phosphatidylserine
-
activation
sodium taurocholate
-
activation
sphingomyelin
-
activation
Triton X-100
UDP-glucose
-
slight stimulation
additional information
-
requirement for phospholipids
-