2.4.2.1: purine-nucleoside phosphorylase

This is an abbreviated version!
For detailed information about purine-nucleoside phosphorylase, go to the full flat file.

Reaction

Synonyms

5'-deoxy-5'-methylthioadenosine phosphorylase II, 5'-methythioadenosine phosphorylase, adenine nucleoside phosphorylase, adenosine phosphorylase, AgPNP, AmPNP, ANP, ApMTAP, apPNP, bovPNP, bPNO, CKP1, cytokinin riboside phosphorylase, DeoD, deoD_1, DgPNP, EC592_06680, EcPNP, flB, GsPNPI, GsPNPII, GtPNP, hPNP, HpPNP, HsPNO, HsPNP, Ino-Guo phosphorylase, inosine phosphorylase, inosine-guanosine phosphorylase, KlacPNP, KLLA0_C16621g, MTAPII, MtbPNP, nucleotide phosphatase (2.4.2.1), PfPNP, phosphorylase, purine nucleoside, PiPNP, PNP, PNP 1, PNP 2, PNP I, PNP II, PNP-II, PNP-Zg, PNPase, pNPI, PNPII, Pu-NPase, punA, PUNP, PUNPI, PUNPII, purine deoxynucleoside phosphorylase, purine deoxyribonucleoside phosphorylase, purine nucleoside orthophosphate ribosyl transferase, purine nucleoside phosphorylase, purine nucleoside phosphorylase 1, purine nucleoside phosphorylase 2, purine nucleoside phosphorylase DeoD, purine nucleoside phosphorylase DeoD-type, purine nucleoside phosphorylase II, purine ribonucleoside phosphorylase, purine-nucleoside phosphorylases II, SalT, SSO2343, TgPNP, TTC0194, TTC1070, TtPNPI, TtPNPII, TvPNP, xanthosine phosphorylase, XAP, xapA, ylmD

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.1 purine-nucleoside phosphorylase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
6	Activating Compound
47462	AA Sequence
56	Application
1	CAS Registry Number
50	Cloned(Commentary)
60	Crystallization (Commentary)
3540	Disease/ Diagnostics
3	Expression
69	General Information
14	General Stability
108	IC50 Value
563	Inhibitors
135	kcat/KM [mM/s]
272	Ki Value [mM]
532	KM Value [mM]
6	Localization
2	Metals/Ions
109	Molecular Weight [Da]
145	Natural Substrates/ Products (Substrates)
7	Organic Solvent Stability
571	Organism
8	Oxidation Stability
22	Pathway
578	PDB ID
65	pH Optimum
12	pH Range
19	pH Stability
114	Protein Variants
74	Purification (Commentary)
20	Reaction
1	Reaction Type
364	Reference
2	Renatured (Commentary)
164	Source Tissue
105	Specific Activity [micromol/min/mg]
14	Storage Stability
924	Substrates and Products (Substrate)
107	Subunits
295	Synonyms
1	Systematic Name
39	Temperature Optimum [°C]
15	Temperature Range [°C]
71	Temperature Stability [°C]
259	Turnover Number [1/s]

pH Stability

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

pH Stability on EC 2.4.2.1 - purine-nucleoside phosphorylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to pH Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

pH STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

10

2 entries

2 - 12

Helicobacter pylori

A0A0G2R4X7

purified recombinant enzyme, 25°C, 1 h. The enzyme is stable retaining over 90% of the initial activity in the pH range 6.0-9.0 at 25°C. Stability decreases rapidly below pH 5.5 and above pH 9.5

759339

5

Cellulomonas sp.

-

37°C, 10 min, 75% loss of activity

489696

5 - 9

Geobacillus stearothermophilus

-

stable from pH 5.0 to pH 9.0

489698

5.5 - 9

Oryctolagus cuniculus

-

40°C, 10 min, stable

489675

6

Cellulomonas sp.

-

37°C, 10 min, 65% loss of activity

489696

6 - 10

Helicobacter pylori

P56463

purified enzyme, 25°C, 90% activity remaining

759175

6 - 8

Pseudoalteromonas sp.

C8CPR9

stable for at least 2 h at 37°C

723802

6.2 - 10

Homo sapiens

-

5 min, stable

489651

6.5

2 entries

7

Cellulomonas sp.

-

37°C, 10 min, 50% loss of activity

489696

7 - 7.3

Enterobacter cloacae

-

80°C, 30 min, stable

489669

7 - 9

Aneurinibacillus migulanus

A0A3G5E8S8

purified recombinant enzyme, 2 h, 60°C, completely stable

759810

8

2 entries

8.5 - 10

Cellulomonas sp.

-

stable in presence of orthophosphate

489708

9

Cellulomonas sp.

-

37°C, 10 min, 20% loss of activity

489696

10

Cellulomonas sp.

-

37°C, 10 min, 10% loss of activity

489696

10

Pseudoalteromonas sp.

A3F8V1

stable for 2.5 h

686625

6.5

Cellulomonas sp.

-

rather unstable below

489708

6.5

Enterobacter cloacae

-

80°C, 30 min, about 75% loss of activity

489669

8

Cellulomonas sp.

-

37°C, 10 min, about 30% loss of maximal activity

489696

8

Enterobacter cloacae

-

80°C, 30 min, about 35% loss of activity

489669