2.4.2.12: nicotinamide phosphoribosyltransferase
This is an abbreviated version!
For detailed information about nicotinamide phosphoribosyltransferase, go to the full flat file.
Word Map on EC 2.4.2.12
-
2.4.2.12
-
adipokines
-
adiponectin
-
leptin
-
obesity
-
adipose
-
resistin
-
adipocytokines
-
nad+
-
obese
-
women
-
adipocytes
-
mellitus
-
cardiovascular
-
visceral
-
necrosis
-
salvage
-
cholesterol
-
sirt1
-
endothelial
-
tnf
-
homa-ir
-
triglyceride
-
apelin
-
sirtuins
-
atherosclerosis
-
c-reactive
-
chemerin
-
interleukin-6
-
anthropometric
-
insulin-mimetic
-
ghrelin
-
circumference
-
overweight
-
lean
-
omentin
-
polycystic
-
adiposity
-
waist
-
vaspin
-
pai-1
-
hs-crp
-
c-peptide
-
obesity-related
-
protein-4
-
retinol-binding
-
adipsin
-
normal-weight
-
index-matched
-
pharmacology
-
irisin
-
medicine
-
nmnats
-
drug development
- 2.4.2.12
- adipokines
- adiponectin
- leptin
- obesity
- adipose
-
resistin
-
adipocytokines
- nad+
-
obese
- women
- adipocytes
- mellitus
- cardiovascular
- visceral
- necrosis
-
salvage
- cholesterol
- sirt1
- endothelial
- tnf
-
homa-ir
- triglyceride
- apelin
- sirtuins
- atherosclerosis
-
c-reactive
- chemerin
- interleukin-6
-
anthropometric
-
insulin-mimetic
- ghrelin
-
circumference
- overweight
-
lean
-
omentin
-
polycystic
-
adiposity
-
waist
- vaspin
- pai-1
-
hs-crp
- c-peptide
-
obesity-related
- protein-4
-
retinol-binding
- adipsin
-
normal-weight
-
index-matched
- pharmacology
-
irisin
- medicine
- nmnats
- drug development
Reaction
Synonyms
eNAMPT, extracellular nicotinamide phosphoribosyltrasferase, iNAMPT, Nam phosphoribosyltransferase, NAmPRTase, Nampt, Nampt/PBEF/Visfatin, Nampt/visfatin, NAMPTA, NAMPTB, NAPRT, nicotinamide mononucleotide pyrophosphorylase, nicotinamide mononucleotide synthetase, nicotinamide phosphoribosyl transferase, nicotinamide phosphoribosyltransferase, nicotinamide phosphoribosyltransferase/Visfatin, NMN pyrophosphorylase, NMN synthetase, NMPRTase, PBEF, phosphoribosyltransferase, nicotinamide, pre-B cell colony enhancing factor, pre-B cell colony enhancing factor(PBEF), pre-B cell colony-enhancing factor, pre-B cell colony-enhancing factor (PBEF), pre-B cell colony-enhancing factor 1, pre-B colony enhancing factor, pre-B-cell colony enhancing factor, pre-B-cell colony-enhancing factor, Visfatin
ECTree
2.4.2.12 nicotinamide phosphoribosyltransferaseAdvanced search results
results (
results (IC50 Value
IC50 Value on EC 2.4.2.12 - nicotinamide phosphoribosyltransferase
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IC50 VALUE [mM] 
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.855
(1Z)-N'-(benzoyloxy)-3-(2-oxo-1,3-benzoxazol-3(2H)-yl)propanimidamide
Homo sapiens
-
at pH 7.5 and 37°C
0.0032
(2E)-1-(4-[[2-(4-fluorophenyl)-1,3-thiazol-4-yl]methyl]piperazin-1-yl)-3-(pyridin-3-yl)prop-2-en-1-one
Homo sapiens
pH and temperature not specified in the publication
0.00078
(2E)-3-(pyridin-3-yl)-1-[4-[4-(trifluoromethoxy)benzyl]piperazin-1-yl]prop-2-en-1-one
Homo sapiens
pH and temperature not specified in the publication
0.00067
(2E)-3-(pyridin-3-yl)-N-[4-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)phenyl]prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00002453
(2E)-3-(pyridin-3-yl)-N-[6-(3-[[4-(trifluoromethyl)phenyl]sulfamoyl]phenyl)hexyl]prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00001163
(2E)-N-(6-[3-[(2,5-dimethylphenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00000508
(2E)-N-(6-[3-[(2-methylphenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.0000097
(2E)-N-(6-[3-[(3-chloro-4-fluorophenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00001228
(2E)-N-(6-[3-[(3-methylphenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00001075
(2E)-N-(6-[3-[(4-chlorophenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00003154
(2E)-N-(6-[3-[(4-ethylphenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.0000092
(2E)-N-(6-[3-[(4-fluorophenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00000978
(2E)-N-(6-[3-[(4-methylphenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00001309
(2E)-N-(6-[3-[(4-phenoxyphenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00000947
(2E)-N-(6-[3-[(4-tert-butylphenyl)sulfamoyl]phenyl]hexyl)-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.01
(2E)-N-[2-(3,4-dimethoxyphenyl)ethyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00094
(2E)-N-[2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-6-yl)oxy]ethyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.01
(2E)-N-[3-(1H-imidazol-1-yl)propyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.0002345
(2E)-N-[3-[3-(phenylsulfamoyl)phenyl]propyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00592
(2E)-N-[3-[4-(phenylsulfamoyl)phenyl]propyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.0000027 - 0.0000049
(2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-(pyridin-3-yl)prop-2-enamide
0.00001777
(2E)-N-[4-[4-(phenylsulfamoyl)phenyl]butyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00001654
(2E)-N-[5-[3-(phenylsulfamoyl)phenyl]pentyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00002839
(2E)-N-[5-[4-(phenylsulfamoyl)phenyl]pentyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00001053
(2E)-N-[6-[3-(phenylsulfamoyl)phenyl]hexyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00001442
(2E)-N-[6-[4-(phenylsulfamoyl)phenyl]hexyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00003132
(2E)-N-[7-[3-(phenylsulfamoyl)phenyl]heptyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.00001641
(2E)-N-[7-[4-(phenylsulfamoyl)phenyl]heptyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.504
(2R,2'R)-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-2,2',3,3'-tetrahydro-4H,4'H-[3,8'-bi-1-benzopyran]-4,4'-dione
Homo sapiens
-
at pH 7.5 and 37°C
0.008
(3R,5R,7R)-N-(4-((E)-3-(pyridin-3-yl)acrylamido)butyl)adamantane-1-carboxamide
Homo sapiens
at 30°C, pH not specified in the publication
0.0066
(4',5,7-trihydroxyflavone)-(3'->8)-(4',5,7-trihydroxyflavone)
Mus musculus
-
pH 7.5, 37°C
0.0175
(4',7-dimethoxy-5-hydroxyflavone)-(3'->8)-(4',7-dimethoxy-5-hydroxyflavone)
Mus musculus
-
pH 7.5, 37°C
0.000057
(E)-N-(4-(1,12-dicarba-closo-dodecaboranyl)amidebutyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.00017
(E)-N-(4-(1,12-dicarba-closo-dodecaboranyl)amidepentyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.000098
(E)-N-(4-(1,7-dicarba-closo-dodecaboranyl)amidebutyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.00032
(E)-N-(4-(1-(1,12-dicarba-closo-dodecaboranyl)piperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.00063
(E)-N-(4-(1-benzoyl-1,12-dicarba-closo-dodecaboran-12-yl)amidebutyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.00018
(E)-N-(4-(1-trimethylsilyl-1,12-dicarba-closododecaboran-12-yl)amidebutyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.01
(E)-N-(4-(4-(1,12-dicarba-closo-dodecaboranecarbonyl)-1,12-dicarba-closo-dodecaboranyl)butyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
IC50 above 0.01 mM, at 30°C, pH not specified in the publication
0.00292
(E)-N-(4-(4-(1,12-dicarba-closo-dodecaboranecarbonyl)-1,7-dicarba-closo-dodecaboranyl)butyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.00451
(E)-N-(4-(4-(1,12-dicarba-closo-dodecaboranyl(hydroxy)methyl)-1,12-dicarba-closo-dodecaboranyl)butyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.00376
(E)-N-(4-(4-(1,7-dicarba-closo-dodecaboranecarbonyl)-1,12-dicarba-closo-dodecaboranyl)butyl)-3-(pyridin-3-yl)acrylamide
Homo sapiens
at 30°C, pH not specified in the publication
0.000062
1,1-dioxo-N-[[4-[(4-pyrrolidin-1-yl-1-piperidyl)sulfonyl]-phenyl]methyl]-2H-pyrido[4,3-e][1,2,4]thiadiazin-3-amine
Homo sapiens
pH and temperature not specified in the publication
0.00025
1-((E)-4-(3-(pyridin-3-yl)acrylamido)hexyl)-1,12-dicarba-closo-dodecaborane
Homo sapiens
at 30°C, pH not specified in the publication
0.00037
1-((E)-4-(3-(pyridin-3-yl)acrylamido)hexyl)-1,2-dicarba-closo-dodecaborane
Homo sapiens
at 30°C, pH not specified in the publication
0.0049
1-((E)-4-(3-(pyridin-3-yl)acrylamido)pentyl)-1,2-dicarba-closo-dodecaborane
Homo sapiens
at 30°C, pH not specified in the publication
0.03
1-(4-(4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl)butyl)-1,2-dicarba-closo-dodecaborane
Homo sapiens
IC50 above 0.03 mM, at 30°C, pH not specified in the publication
0.03
1-(4-(4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl)pentyl)-1,2-dicarba-closo-dodecaborane
Homo sapiens
IC50 above 0.03 mM, at 30°C, pH not specified in the publication
0.03
1-(5-(1H-pyrrolo[3,2-c]pyridine-2-carboxamido)butyl)-1,2-dicarba-closo-dodecaborane
Homo sapiens
IC50 above 0.03 mM, at 30°C, pH not specified in the publication
0.03
1-(5-(1H-pyrrolo[3,2-c]pyridine-2-carboxamido)pentyl)-1,2-dicarba-closo-dodecaborane
Homo sapiens
IC50 above 0.03 mM, at 30°C, pH not specified in the publication
0.0000439
1-(pyridin-3-ylmethyl)-3-[4-(pyrrolidin-1-ylsulfonyl)phenyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000324
1-([1,1'-biphenyl]-2-yl)-3-(7-(4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl)heptyl)urea
Mus musculus
at pH 7.5 and 37°C
0.002
1-methyl-N-[4-(phenylsulfonyl)benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000003
1-[(6-aminopyridin-3-yl)methyl]-3-[4-(phenylsulfonyl)phenyl]urea
Homo sapiens
pH and temperature not specified in the publication
0.005
1-[2-(naphthalen-2-yloxy)ethyl]-3-(pyridin-3-ylmethyl)urea
Homo sapiens
pH and temperature not specified in the publication
0.00987
1-[3-(piperidin-1-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000217
1-[4-(morpholin-4-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000845
1-[4-(piperazin-1-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000422
1-[4-(piperidin-1-ylcarbonyl)phenyl]-3-(pyridin-3-ylmethyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.01453
1-[4-(piperidin-1-yloxy)phenyl]-3-(pyridin-3-ylmethyl)guanidine
Homo sapiens
-
at pH 7.5 and 37°C
0.0000989
1-[4-(piperidin-1-yloxy)phenyl]-3-(pyridin-3-ylmethyl)urea
Homo sapiens
-
at pH 7.5 and 37°C
0.000765
1-[4-(piperidin-1-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)guanidine
Homo sapiens
-
at pH 7.5 and 37°C
0.0000201
1-[4-(piperidin-1-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000964
1-[4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]-3-(pyridin-3-ylmethyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0038
1H-indol-2-yl(4-[[3-(pyridin-3-yl)-1H-pyrazol-5-yl]carbonyl]piperazin-1-yl)methanone
Homo sapiens
pH and temperature not specified in the publication
0.0000385
2'-([7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]carbamoyl)[1,1'-biphenyl]-2-carboxylic acid
Homo sapiens
pH and temperature not specified in the publication
0.0005
2'-([7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]carbamoyl)[1,1'-biphenyl]-3-carboxylic acid
Homo sapiens
IC50 above 0.0005 mM, pH and temperature not specified in the publication
0.0005
2'-([7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]carbamoyl)[1,1'-biphenyl]-4-carboxylic acid
Homo sapiens
IC50 above 0.0005 mM, pH and temperature not specified in the publication
0.0000879
2'-[(aminooxy)carbonyl]-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl][1,1'-biphenyl]-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000206
2-(4-[[4-(1-ethoxyethenyl)piperidin-1-yl]methyl]-1H-1,2,3-triazol-1-yl)-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000247
2-(4-[[4-(propan-2-yl)piperazin-1-yl]methyl]-1H-1,2,3-triazol-1-yl)-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000738
2-(4-[[bis(2-hydroxyethyl)amino]methyl]-1H-1,2,3-triazol-1-yl)-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000285
2-(pyridin-3-yl)-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000025
2-cyano-1-[4-(phenylsulfonyl)benzyl]-3-pyridin-4-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.0019
2-[4-[(4-chlorophenyl)sulfamoyl]phenoxy]-N-(pyridin-3-ylmethyl)acetamide
Homo sapiens
pH and temperature not specified in the publication
0.0000418
2-[4-[(4-hydroxypiperidin-1-yl)methyl]-1H-1,2,3-triazol-1-yl]-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000136
2-[4-[(4-methylpiperazin-1-yl)methyl]-1H-1,2,3-triazol-1-yl]-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000424
2-[4-[(dimethylamino)methyl]-1H-1,2,3-triazol-1-yl]-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000496
2-[4-[(morpholin-4-yl)methyl]-1H-1,2,3-triazol-1-yl]-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000171
2-[4-[(piperidin-1-yl)methyl]-1H-1,2,3-triazol-1-yl]-N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000156
3-(1-(4-(2-([1,1'-biphenyl]-2-yloxy)ethyl)benzyl)-1H-1,2,3-triazol-4-yl)pyridine
Mus musculus
at pH 7.5 and 37°C
0.0000038
3-(1-(6-([1,1'-biphenyl]-2-yloxy)hexyl)-1H-1,2,3-triazol-4-yl)-pyridine
Mus musculus
at pH 7.5 and 37°C
0.0000081
3-(1-(7-(4-([1,1'-biphenyl]-2-yl)-1H-1,2,3-triazol-1-yl)-heptyl)-1H-1,2,3-triazol-4-yl)pyridine
Mus musculus
at pH 7.5 and 37°C
0.0000313
3-(1-(7-([1,1'-biphenyl]-2-yloxy)heptyl)-1H-1,2,3-triazol-4-yl)pyridine
Mus musculus
at pH 7.5 and 37°C
0.0000254
3-(1-(8-([1,1'-biphenyl]-2-yloxy)octyl)-1H-1,2,3-triazol-4-yl)-pyridine
Mus musculus
at pH 7.5 and 37°C
4.162
4-chloro-N-[(5-[[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]sulfamoyl]thiophen-2-yl)methyl]benzamide
Homo sapiens
-
at pH 7.5 and 37°C
0.00022
4-[[(2E)-3-(pyridin-3-yl)prop-2-enoyl]amino]-N-(2,2,2-trifluoroethyl)benzamide
Homo sapiens
pH and temperature not specified in the publication
0.00032
5-(3,4-dichlorobenzyl)-4-oxo-N-(pyridin-3-ylmethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.23
7-chloro-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide
Homo sapiens
pH and temperature not specified in the publication
0.166
ethyl [(E)-[4-(piperidine-1-sulfonyl)anilino][[(pyridin-3-yl)methyl]amino]methylidene]carbamate
Homo sapiens
-
at pH 7.5 and 37°C
0.0013
gallotanine
Mus musculus
-
i.e. (2R,3S,5R,6S)-tetrahydro-2H-pyran-2,3,4,5,6-pentaylpentakis(oxycarbonyl-5,6-dihydroxybenzene-3,1-diyl) pentakis(3,4,5-trihydroxybenzoate), pH 7.5, 37°C
0.0000017
N''-cyano-N-([4-[6-(morpholin-4-yl)pyridine-3-sulfonyl]phenyl]methyl)-N'-pyridin-4-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000044
N''-cyano-N-pyridin-4-yl-N'-([4-[3-(trifluoromethoxy)benzene-1-sulfonyl]phenyl]methyl)guanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000024
N''-cyano-N-pyridin-4-yl-N'-([4-[3-(trifluoromethyl)benzene-1-sulfonyl]phenyl]methyl)guanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000036
N''-cyano-N-pyridin-4-yl-N'-[[4-(quinoline-8-sulfonyl)phenyl]methyl]guanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000006
N''-cyano-N-[[4-(3,5-difluorobenzene-1-sulfonyl)phenyl]methyl]-N'-pyridin-4-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000019
N''-cyano-N-[[4-(3-methoxybenzene-1-sulfonyl)phenyl]methyl]-N'-pyridin-4-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000044
N''-cyano-N-[[4-(8-oxa-3-azabicyclo[3.2.1]octane-3-sulfonyl)phenyl]methyl]-N'-pyridin-3-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000024
N''-cyano-N-[[4-(8-oxa-3-azabicyclo[3.2.1]octane-3-sulfonyl)phenyl]methyl]-N'-pyridin-4-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000054
N''-cyano-N-[[4-(cyclohexanesulfonyl)phenyl]methyl]-N'-pyridin-4-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.0000075
N''-cyano-N-[[4-(phenylmethanesulfonyl)phenyl]methyl]-N'-pyridin-4-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.000002
N''-cyano-N-[[4-(pyridine-3-sulfonyl)phenyl]methyl]-N'-pyridin-4-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.01
N-(2-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-oxoethyl)-3-methylthiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00095
N-(2-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-oxoethyl)-5-methylthiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000418
N-(4-butylphenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000014
N-(4-[4-[(1H-benzimidazol-2-yl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000099
N-(4-[4-[(2,6-difluorophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000157
N-(4-[4-[(2-chlorophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000123
N-(4-[4-[(2-fluorophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000124
N-(4-[4-[(2-methylphenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000126
N-(4-[4-[(3-chlorophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000089
N-(4-[4-[(3-fluorophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000168
N-(4-[4-[(3-methylphenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000199
N-(4-[4-[(4-aminophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000242
N-(4-[4-[(4-bromophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000798
N-(4-[4-[(4-butylphenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000137
N-(4-[4-[(4-chlorophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.000012
N-(4-[4-[(4-fluorophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000105
N-(4-[4-[(4-methylphenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000197
N-(4-[4-[(4-nitrophenyl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000191
N-(4-[4-[(furan-2-yl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000487
N-(4-[4-[(furan-3-yl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000295
N-(4-[4-[(naphthalen-2-yl)methyl]piperazine-1-sulfonyl]phenyl)-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.000099
N-(4-[[1-(propan-2-yl)-1H-pyrazol-4-yl]sulfonyl]benzyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000077
N-(4-[[3-(trifluoromethoxy)phenyl]sulfonyl]benzyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000061
N-(4-[[3-(trifluoromethyl)phenyl]sulfonyl]benzyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00001
N-(4-[[5-(trifluoromethyl)pyridin-3-yl]sulfonyl]benzyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000031
N-(7-(4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl)heptyl)-[1,1'-biphenyl]-2-carboxamide
Mus musculus
at pH 7.5 and 37°C
0.0000031
N-(7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl)[1,1'-biphenyl]-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000047
N-(8-(4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl)octyl)biphenyl-2-sulfonamide
Mus musculus
at pH 7.5 and 37°C
0.002
N-(pyridin-4-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000269
N-([1,1'-biphenyl]-2-yl)-8-(5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)octanamide
Mus musculus
at pH 7.5 and 37°C
0.0000499
N-([1,1'-biphenyl]-2-yl)-8-(5-(pyridin-3-yl)isoxazol-3-yl)-octanamide
Mus musculus
at pH 7.5 and 37°C
0.0000102
N-([1,1'-biphenyl]-2-yl)-8-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]octanamide
Mus musculus
at pH 7.5 and 37°C
0.00044
N-([4-[4-(oxetan-3-yl)piperazine-1-sulfonyl]phenyl]methyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0003
N-([4-[4-(pyrrolidin-1-yl)piperidine-1-sulfonyl]phenyl]methyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000012
N-([4-[6-(dimethylamino)pyridine-3-sulfonyl]phenyl]methyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000045
N-([4-[6-(morpholin-4-yl)pyridine-3-sulfonyl]phenyl]methyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000196
N-benzyl-4-[[(pyridin-3-ylmethyl)carbamothioyl]amino]benzenesulfonamide
Homo sapiens
-
at pH 7.5 and 37°C
0.000022
N-phenyl-4-[[(pyridin-3-ylmethyl)carbamothioyl]amino]benzenesulfonamide
Homo sapiens
-
at pH 7.5 and 37°C
0.0000098
N-[(pyridin-3-yl)methyl]-N'-(4-[4-[(pyridin-3-yl)methyl]piperazine-1-sulfonyl]phenyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000137
N-[(pyridin-3-yl)methyl]-N'-(4-[4-[(pyridin-4-yl)methyl]piperazine-1-sulfonyl]phenyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000388
N-[(pyridin-3-yl)methyl]-N'-(4-[4-[(thiophen-2-yl)methyl]piperazine-1-sulfonyl]phenyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000225
N-[(pyridin-3-yl)methyl]-N'-(4-[4-[(thiophen-3-yl)methyl]piperazine-1-sulfonyl]phenyl)thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000369
N-[(pyridin-3-yl)methyl]-N'-[4-(4-[[4-(trifluoromethoxy)phenyl]methyl]piperazine-1-sulfonyl)phenyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000237
N-[(pyridin-3-yl)methyl]-N'-[4-(4-[[4-(trifluoromethyl)phenyl]methyl]piperazine-1-sulfonyl)phenyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000177
N-[(pyridin-3-yl)methyl]-N'-[4-[4-(pyridin-2-yl)piperazine-1-sulfonyl]phenyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0014
N-[2-(3,4-dimethoxyphenyl)ethyl]-1-benzofuran-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0053
N-[2-(3,4-dimethoxyphenyl)ethyl]-3-methylthiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00086
N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methylthiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.01
N-[2-(3,4-dimethoxyphenyl)ethyl]-5-nitrothiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.001
N-[3-(1H-imidazol-1-yl)propyl]-1-benzofuran-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0011
N-[3-(1H-imidazol-1-yl)propyl]-1-benzothiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.01
N-[3-(1H-imidazol-1-yl)propyl]-3-methylthiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00017
N-[3-(1H-imidazol-1-yl)propyl]-5-methylthiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.01
N-[3-(1H-imidazol-1-yl)propyl]-5-nitrothiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000051
N-[4-(1-propyl-1H-pyrazole-3-sulfonyl)phenyl]-2-(pyridin-3-yl)cyclopropane-1-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000405
N-[4-(4-acetylpiperazine-1-sulfonyl)phenyl]-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000009
N-[4-(4-benzylpiperazine-1-sulfonyl)phenyl]-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0000142
N-[4-(4-cyclohexylpiperazine-1-sulfonyl)phenyl]-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.00037
N-[4-(morpholin-4-ylsulfonyl)benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000066
N-[4-(phenylsulfonyl)benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.002
N-[4-(phenylsulfonyl)benzyl]-1H-pyrazolo[3,4-c]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.002
N-[4-(phenylsulfonyl)benzyl]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000029
N-[4-(phenylsulfonyl)benzyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000043
N-[4-(phenylsulfonyl)benzyl]-5-(pyridin-3-yl)-1H-pyrazole-3-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.018
N-[4-(phenylsulfonyl)benzyl]imidazo[1,2-a]pyridine-6-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.002
N-[4-(piperidin-1-ylsulfonyl)benzyl]-1H-indazole-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000088
N-[4-(piperidin-1-ylsulfonyl)benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.028
N-[4-(piperidin-1-ylsulfonyl)benzyl]imidazo[1,2-a]pyridine-6-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000082
N-[4-(quinolin-3-ylsulfonyl)benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00019
N-[4-[(1-ethyl-1H-pyrazol-4-yl)sulfonyl]benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00001
N-[4-[(1-propyl-1H-pyrazol-4-yl)sulfonyl]benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000079
N-[4-[(3,5-difluorophenyl)sulfonyl]benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00041
N-[4-[(4-cyanopiperidin-1-yl)sulfonyl]benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00041
N-[4-[(4-hydroxypiperidin-1-yl)sulfonyl]benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
6.443
N-[4-[(4E)-4-(2,3-dimethoxybenzylidene)-5-oxo-4,5-dihydro-1,3-oxazol-2-yl]phenyl]thiophene-2-carboxamide
Homo sapiens
-
at pH 7.5 and 37°C
0.000011
N-[4-[(5-chloropyridin-3-yl)sulfonyl]benzyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000154
N-[4-[4-(4-methylphenyl)piperazine-1-sulfonyl]phenyl]-N'-[(pyridin-3-yl)methyl]thiourea
Homo sapiens
-
at pH 7.5 and 37°C
0.0005
N-[7-[4-(1-oxo-1lambda(5)-pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl][1,1'-biphenyl]-2-carboxamide
Homo sapiens
IC50 above 0.0005 mM, pH and temperature not specified in the publication
0.0000034
N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]-2-(1H-1,2,3-triazol-1-yl)benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000425
N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]-2-(1H-1,2,3-triazol-4-yl)benzamide
Homo sapiens
pH and temperature not specified in the publication
0.0000254
N-[7-[4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl]heptyl]-2-[4-[(pyrrolidin-1-yl)methyl]-1H-1,2,3-triazol-1-yl]benzamide
Homo sapiens
pH and temperature not specified in the publication
0.00039
N-[[4-(4-aminopiperidine-1-sulfonyl)phenyl]methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0004
N-[[4-(4-methoxypiperidine-1-sulfonyl)phenyl]methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00011
N-[[4-(7-oxa-2-azaspiro[3.5]nonane-2-sulfonyl)phenyl]methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000063
N-[[4-(benzenesulfonyl)phenyl]methyl]-1,1-dioxo-2H-pyrido[4,3-e][1,2,4]thiadiazin-3-amine
Homo sapiens
pH and temperature not specified in the publication
0.0013
N-[[4-(benzenesulfonyl)phenyl]methyl]-1H-pyrazolo[4,3-b]pyridine-5-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000022
N-[[4-(benzenesulfonyl)phenyl]methyl]-N''-cyano-N'-pyridin-3-ylguanidine
Homo sapiens
pH and temperature not specified in the publication
0.03
tert-butyl ((1,12-dicarba-closo-dodecaboranylamido)propyl)carbamate
Homo sapiens
IC50 above 0.03 mM, at 30°C, pH not specified in the publication
0.0000217
tert-butyl 4-[4-([[(pyridin-3-yl)methyl]carbamothioyl]amino)benzene-1-sulfonyl]piperazine-1-carboxylate
Homo sapiens
-
at pH 7.5 and 37°C
0.002
tert-butyl trans-1-(2-(pyridin-3-yl)cyclopropanecarbonyl)-hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate
Homo sapiens
pH and temperature not specified in the publication
0.002
tert-butyl trans-6-(2-(pyridin-3-yl)cyclopropanecarbonyl)-2,6-diazaspiro[3.4]octane-2-carboxylate
Homo sapiens
pH and temperature not specified in the publication
0.00046
trans-(R,R)-N-(4-((1-isopropyl-1H-pyrazol-4-yl)sulfonyl)-phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000005
trans-(S,S)-N-(4-((1-isopropyl-1H-pyrazol-4-yl)sulfonyl)-phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000051
trans-(S,S)-N-(4-((1-propyl-1H-pyrazol-4-yl)sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.002
trans-2-(6-aminopyridin-3-yl)-N-(4-(phenylsulfonyl)benzyl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000049
trans-2-(6-aminopyridin-3-yl)-N-(4-(phenylsulfonyl)phenyl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00001
trans-2-(pyridin-3-yl)-N-(4-((1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl)sulfonyl)phenyl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000066
trans-2-(pyridin-3-yl)-N-(4-((1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)sulfonyl)phenyl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000095
trans-2-(pyridin-3-yl)-N-(4-((3-(trifluoromethoxy)phenyl)-sulfonyl)phenyl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.00001
trans-2-(pyridin-3-yl)-N-(4-((3-(trifluoromethyl)phenyl)-sulfonyl)phenyl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000036
trans-2-(pyridin-3-yl)-N-(4-((tetrahydro-2H-pyran-4-yl)-sulfonyl)phenyl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0016
trans-2-phenyl-N-(pyridin-4-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000002
trans-N-(4-((1-(2-Hydroxy-2-methylpropyl)-1H-pyrazol-4-yl)-sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000009
trans-N-(4-((1-ethyl-1H-pyrazol-4-yl)sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000001
trans-N-(4-((1-Isopropyl-1H-pyrazol-4-yl)sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000038
trans-N-(4-((1-isopropyl-3-methyl-1H-pyrazol-4-yl)sulfonyl)-phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000011
trans-N-(4-((1-isopropyl-5-methyl-1H-pyrazol-4-yl)sulfonyl)-phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000072
trans-N-(4-((1-propyl-1H-pyrazol-4-yl)sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000012
trans-N-(4-((3,5-difluorophenyl)sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000044
trans-N-(4-((3-(methylsulfonyl)phenyl)sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000012
trans-N-(4-((6-methylpyridin-3-yl)sulfonyl)phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000047
trans-N-(4-(1-benzoylpiperidin-4-yl)butyl)-2-(pyridin-3-yl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000088
trans-N-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)-phenyl)-2-(pyridin-3-yl)cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.000021
trans-N-(4-(morpholinosulfonyl)phenyl)-2-(pyridin-3-yl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0015
trans-N-(4-(phenylsulfonyl)benzyl)-2-(pyridin-3-yl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.002
trans-N-(4-(phenylsulfonyl)benzyl)-2-(pyridin-4-yl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000078
trans-N-(4-(phenylsulfonyl)phenyl)-2-(pyridin-3-yl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0013
trans-N-(4-(phenylsulfonyl)phenyl)-2-(pyridin-4-yl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0000076
trans-N-(6-(4-chlorophenoxy)hexyl)-2-(pyridin-3-yl)-cyclopropanecarboxamide
Homo sapiens
pH and temperature not specified in the publication
0.0002427
[4-(diphenylmethyl)piperazin-1-yl][5-(pyridin-3-yl)-1H-pyrazol-3-yl]methanone
Homo sapiens
pH and temperature not specified in the publication
0.0000027
(2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-(pyridin-3-yl)prop-2-enamide
Homo sapiens
pH and temperature not specified in the publication
0.0000049
(2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-(pyridin-3-yl)prop-2-enamide
Mus musculus
at pH 7.5 and 37°C
0.0000009
FK-866
Mus musculus
-
i.e. (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-phenylprop-2-enamide, pH 7.5, 37°C
0.00015
N-[2-(3,4-dimethoxyphenyl)ethyl]-1-benzothiophene-2-carboxamide
Homo sapiens
pH and temperature not specified in the publication
0.149
N-[2-(3,4-dimethoxyphenyl)ethyl]-1-benzothiophene-2-carboxamide
Homo sapiens
-
at pH 7.5 and 37°C
