Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.2.14: amidophosphoribosyltransferase

This is an abbreviated version!
For detailed information about amidophosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.14

Reaction

5-phospho-beta-D-ribosylamine
+
diphosphate
+
L-glutamate
=
L-glutamine
+
5-phospho-alpha-D-ribose 1-diphosphate
+
H2O

Synonyms

5'-phosphoribosylpyrophosphate amidotransferase, 5-phosphoribosyl-1-pyrophosphate amidotransferase, 5-phosphoribosylpyrophosphate amidotransferase, 5-phosphororibosyl-1-pyrophosphate amidotransferase, ADE4, alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase, amido phosphoribosyltransferase, amidotransferase, phosphoribosyl pyrophosphate, APRT, ATASE, AtGPRT, Gln phosphoribosylpyrophosphate amidotransferase, glutamine 5-phosphoribosylpyrophosphate amidotransferase, glutamine phosphoribosyl pyrophosphate amidotransferase, glutamine phosphoribosylpyrophosphate amidotransferase, glutamine ribosylpyrophosphate 5-phosphate amidotransferase, GPAT, GPATase, GPRAT, GPRAT2, phosphoribose pyrophosphate amidotransferase, phosphoribosyl amidotransferase, phosphoribosyl pyrophosphate amidotransferase, phosphoribosylamidotransferase, phosphoribosyldiphosphate 5-amidotransferase, phosphoribosylpyrophosphate glutamyl amidotransferase, PPAT, PRAT, PurF

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.14 amidophosphoribosyltransferase

KI Value

KI Value on EC 2.4.2.14 - amidophosphoribosyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.053 - 0.058
1-alpha-diphosphoryl-2-alpha,3-alpha-dihydroxy-4-beta-cyclopentane-methanol-5-phosphate
0.02327
2,4-diamino-6-(3,4,5-trimethoxyanilino)-methylpyrido[3,2-d]pyrimidine
pH and temperature not specified in the publication
0.00331
2,4-diamino-6-(3,4,5-trimethoxybenzyl)-5,6,7,8-tetrahydro-quinazoline
pH and temperature not specified in the publication
0.39
5'-p-fluorosulfonylbenzoyladenosine
-
-
0.1167
5-((4-carboxy-4-(4-(((2,4-diaminopyrido[3,2-d]pyrimidine-6-yl)methyl)amino)benzamido)butyl)carbamoyl)isophthalic acid
pH and temperature not specified in the publication
0.0034
6-diazo-5-oxo-L-norleucine
-
-
0.038 - 0.64
ADP
-
-
0.00131 - 2.5
AMP
0.031 - 1.1
ATP
-
-
4
azaserine
-
-
0.005293
DAS734
at pH 7.8, temperature not specified in the publication
0.65
diphosphate
-
-
0.38 - 5.4
GDP
-
-
30
glutamate
-
-
0.086 - 0.35
GMP
-
-
0.18 - 3.5
IMP
-
-
0.00174
lomexterol
pH and temperature not specified in the publication
0.01074
methotrexate
pH and temperature not specified in the publication
3.3
NH3
-
-
16
NH4+
-
-
0.00528
pipretixin
pH and temperature not specified in the publication
0.066
piritrexim
-
-
1.2
XMP
-
-