2.4.2.17: ATP phosphoribosyltransferase

This is an abbreviated version!
For detailed information about ATP phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

1-(5-phospho-D-ribosyl)-ATP:pyrophosphate phospho-alpha-D-ribosyltransferase, adenosine 5'-triphosphate phosphoribosyltransferase, adenosine triphosphate phosphoribosyltransferase, adenosine-triphosphate phosphoribosyltransferase, ATP phosphoribosyl transferase, ATP phosphoribosyl transferase complex, ATP phosphoribosyltransferase, ATP-phosphoribosyl transferase, ATP-phosphoribosyltransferase, ATP-PRT, ATP-PRT1, ATP-PRT2, ATP-PRTase, ATPPRT, HisG, HisGL, N-1-(5'-phosphoribosyl)-ATP transferase, phosphoribosyl ATP synthetase, phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase, phosphoribosyl-ATP pyrophosphorylase, phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase, phosphoribosyladenosine triphosphate pyrophosphorylase, phosphoribosyladenosine triphosphate synthetase, phosphoribosyltransferase, adenosine triphosphate

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.17 ATP phosphoribosyltransferase

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Results	in table
3	Activating Compound
36759	AA Sequence
3	Application
1	CAS Registry Number
20	Cloned(Commentary)
12	Crystallization (Commentary)
2	Expression
1	General Information
5	General Stability
14	IC50 Value
101	Inhibitors
18	kcat/KM [mM/s]
28	Ki Value [mM]
51	KM Value [mM]
1	Localization
19	Metals/Ions
18	Molecular Weight [Da]
55	Natural Substrates/ Products (Substrates)
253	Organism
6	Pathway
100	PDB ID
11	pH Optimum
1	pH Range
1	pH Stability
32	Protein Variants
25	Purification (Commentary)
8	Reaction
1	Reaction Type
49	Reference
13	Source Tissue
9	Specific Activity [micromol/min/mg]
5	Storage Stability
83	Substrates and Products (Substrate)
31	Subunits
77	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
1	Temperature Range [°C]
8	Temperature Stability [°C]
29	Turnover Number [1/s]

Cloned

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Cloned on EC 2.4.2.17 - ATP phosphoribosyltransferase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

-

4 entries

codon adapted to Escherichia coli, synthetically prepared, His-tagged protein expressed in Escherichia coli BL21(DE3)pLysS

Mycobacterium tuberculosis

-

721673

expressed in Escherichia coli

Mycobacterium tuberculosis

-

637675

expressed in Escherichia coli BL21 gold cells

Medicago truncatula

G7JFL4

758758

expressed in Escherichia coli BL21(DE3) cells

2 entries

expressed in Escherichia coli C43(DE3) cells

Psychrobacter arcticus

Q4FQF7

758806

expressed in Escherichia coli ER2556 cells

Corynebacterium glutamicum

Q9Z472

736541

expression in Escherichia coli

Arabidopsis thaliana

Q9S762

637673

expression of selenomethionine-labeled enzyme in strain B834(DE3)

Escherichia coli

P60757

659707

His-tagged protein expressed in Escherichia coli BL21(DE3)

Corynebacterium glutamicum

Q9Z472

721765

overexpression of an Alyssum lesbiacum ATP-PRT cDNA in transgenic Arabidopsis thaliana increases the pool of free His up to 15fold in shoot tissue, without affecting the concentration of any other amino acid. His-overproducing lines also display elevated tolerance to Ni but do not exhibit increased Ni concentrations in either xylem sap or shoot tissue, suggesting that additional factors are necessary to recapitulate the complete hyperaccumulator phenotype

3 entries

overexpression of subunits HisGs and HisZ comprising complex in Escherichia coli strain BL21(DE3) as wild-type, or in strain B834 as selenomethionine-labeled complex

Lactococcus lactis

-

659495

separate expression of subunits HisGs and HisZ in Escherichia coli strain BL21(DE3) as wild-type, or in strain B834 as selenomethionine-labeled proteins

Thermotoga maritima

-

659965

-

Corynebacterium glutamicum

-

637672

-

Mycobacterium tuberculosis

P9WMN1

758560

-

Campylobacter jejuni

Q5HSJ4

758560

-

Lactococcus lactis

Q02129

758560

expressed in Escherichia coli BL21(DE3) cells

Campylobacter jejuni

Q9PM78

737208

expressed in Escherichia coli BL21(DE3) cells

Campylobacter jejuni

Q5HSJ4

758757, 758921

overexpression of an Alyssum lesbiacum ATP-PRT cDNA in transgenic Arabidopsis thaliana increases the pool of free His up to 15fold in shoot tissue, without affecting the concentration of any other amino acid. His-overproducing lines also display elevated tolerance to Ni but do not exhibit increased Ni concentrations in either xylem sap or shoot tissue, suggesting that additional factors are necessary to recapitulate the complete hyperaccumulator phenotype

Odontarrhena lesbiaca

Q56UT2, Q56UT3

682318

overexpression of an Alyssum lesbiacum ATP-PRT cDNA in transgenic Arabidopsis thaliana increases the pool of free His up to 15fold in shoot tissue, without affecting the concentration of any other amino acid. His-overproducing lines also display elevated tolerance to Ni but do not exhibit increased Ni concentrations in either xylem sap or shoot tissue, suggesting that additional factors are necessary to recapitulate the complete hyperaccumulator phenotype

Alyssum montanum

Q56US5

682318

overexpression of an Alyssum lesbiacum ATP-PRT cDNA in transgenic Arabidopsis thaliana increases the pool of free His up to 15fold in shoot tissue, without affecting the concentration of any other amino acid. His-overproducing lines also display elevated tolerance to Ni but do not exhibit increased Ni concentrations in either xylem sap or shoot tissue, suggesting that additional factors are necessary to recapitulate the complete hyperaccumulator phenotype

Odontarrhena serpyllifolia

-

682318