2.4.2.2: pyrimidine-nucleoside phosphorylase

This is an abbreviated version!
For detailed information about pyrimidine-nucleoside phosphorylase, go to the full flat file.

Reaction

Synonyms

AmPyNP, BbPyNP, BfPyNP, BsPyNP, deoA, EC 2.4.2.23, GsPyNP, GtPyNP, LpPyNP, nucleoside phosphorylase, PDP, phosphorylase, pyrimidine nucleoside, Py-NPase, PYNP, pynpase, pyrimidine nucleoside phosphorylase, pyrimidine ribonucleoside phosphorylase, pyrimidine-nucleoside phosphorylase, pyrimidine/purine nucleoside phosphorylase, TTHA1771, TtPyNP, udp, UPase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.2 pyrimidine-nucleoside phosphorylase

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Results	in table
1	Activating Compound
13423	AA Sequence
8	Application
1	CAS Registry Number
18	Cloned(Commentary)
6	Crystallization (Commentary)
85	Disease/ Diagnostics
1	Expression
9	General Information
3	General Stability
10	IC50 Value
7	Inhibitors
12	kcat/KM [mM/s]
2	Ki Value [mM]
50	KM Value [mM]
7	Molecular Weight [Da]
71	Natural Substrates/ Products (Substrates)
136	Organism
1	Oxidation Stability
5	Pathway
10	PDB ID
19	pH Optimum
3	pH Range
2	pH Stability
6	Protein Variants
11	Purification (Commentary)
4	Reaction
5	Reaction Type
45	Reference
1	Renatured (Commentary)
2	Source Tissue
15	Specific Activity [micromol/min/mg]
2	Storage Stability
194	Substrates and Products (Substrate)
11	Subunits
62	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
5	Temperature Range [°C]
19	Temperature Stability [°C]
20	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.4.2.2 - pyrimidine-nucleoside phosphorylase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.113 - 0.188

3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate

4 entries

0.000003 - 0.000005

5-benzylacyclouridine

2 entries

0.5

5-chloro-6-(1-[2-iminopyrrolidinyl]methyl)uracil

2 entries

0.03 - 0.06

7-deazaxanthine

2 entries

0.113

3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate

Mycoplasma hyorhinis

-

substrate deoxythymidine, pH 7.6, 37°C

721554

0.128

3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate

Mycoplasma hyorhinis

-

substrate 5-fluorodeoxyuridine, pH 7.6, 37°C

721554

0.159

3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate

Mycoplasma hyorhinis

-

substrate 5-iododeoxyuridine pH 7.6, 37°C

721554

0.188

3,5-bis-(4-chlorobenzoyl)-alpha-D-ribose 1-phosphate

Mycoplasma hyorhinis

-

substrate uridine, pH 7.6, 37°C

721554

0.000003

5-benzylacyclouridine

Mycoplasma hyorhinis

-

substrate uridine, pH 7.6, 37°C

721540

0.000005

5-benzylacyclouridine

Mycoplasma hyorhinis

-

substrate deoxythymidine, pH 7.6, 37°C

721540

0.5

5-chloro-6-(1-[2-iminopyrrolidinyl]methyl)uracil

Mycoplasma hyorhinis

-

substrate deoxythymidine, pH 7.6, 37°C

721540

0.5

5-chloro-6-(1-[2-iminopyrrolidinyl]methyl)uracil

Mycoplasma hyorhinis

-

substrate uridine, pH 7.6, 37°C

721540

0.03

7-deazaxanthine

Mycoplasma hyorhinis

-

substrate deoxythymidine, pH 7.6, 37°C

721540

0.06

7-deazaxanthine

Mycoplasma hyorhinis

-

substrate uridine, pH 7.6, 37°C

721540