2.4.2.22: xanthine phosphoribosyltransferase
This is an abbreviated version!
For detailed information about xanthine phosphoribosyltransferase, go to the full flat file.
Word Map on EC 2.4.2.22
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2.4.2.22
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purine
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salvage
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falciparum
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plasmodium
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6-oxopurine
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phosphoribosylation
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phosphoribosyltransferases
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tritrichomonas
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prtases
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2.4.2.8
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cho-k1-bh4
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hgprts
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2.7.1.20
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psv2-gpt
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medicine
- 2.4.2.22
- purine
-
salvage
- falciparum
- plasmodium
-
6-oxopurine
-
phosphoribosylation
-
phosphoribosyltransferases
-
tritrichomonas
-
prtases
-
2.4.2.8
-
cho-k1-bh4
- hgprts
-
2.7.1.20
-
psv2-gpt
- medicine
Reaction
Synonyms
5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase, EcXGPRT, HGXPRT, hypoxanthine-guanine-(xanthine) phosphoribosyltransferase, hypoxanthine-guanine-xanthine phosphoribosyltransferase, More, Pf HGXPRT, phosphoribosyltransferase, xanthine, ttha0535, TtXPRT, Xan phosphoribosyltransferase, xanthine phosphoribosyltransferase, xanthine PRT, xanthine-guanine PRT, xanthosine 5'-phosphate pyrophosphorylase, xanthylate pyrophosphorylase, xanthylic pyrophosphorylase, XGPRT
ECTree
2.4.2.22 xanthine phosphoribosyltransferaseAdvanced search results
results (
results (KM Value
KM Value on EC 2.4.2.22 - xanthine phosphoribosyltransferase
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0034
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E198D/E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM hypoxanthine
0.0073
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E198D/E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM xanthine
0.0162
5-phospho-alpha-D-ribose 1-diphosphate
-
wild-type, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM xanthine
0.0181
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM hypoxanthine
0.023
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E215Q, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM hypoxanthine
0.0244
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM xanthine
0.0251
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E198D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM hypoxanthine
0.0288
5-phospho-alpha-D-ribose 1-diphosphate
-
wild-type, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM hypoxanthine
0.0382
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E198D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM xanthine
0.045
5-phospho-alpha-D-ribose 1-diphosphate
-
mutant E215Q, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM xanthine
0.053
5-phospho-alpha-D-ribose 1-diphosphate
-
IMP-activated wild type enzyme, at pH 7.4, temperature not specified in the publication
0.094
5-phospho-alpha-D-ribose 1-diphosphate
-
IMP-activated mutant enzyme W181Y, at pH 7.4, temperature not specified in the publication
0.233
5-phospho-alpha-D-ribose 1-diphosphate
-
IMP-activated mutant enzyme W181F, at pH 7.4, temperature not specified in the publication
0.251
5-phospho-alpha-D-ribose 1-diphosphate
-
IMP-activated mutant enzyme W181S, at pH 7.4, temperature not specified in the publication
1.084
5-phospho-alpha-D-ribose 1-diphosphate
-
unactivated wild type enzyme, at pH 7.4, temperature not specified in the publication
2.286
5-phospho-alpha-D-ribose 1-diphosphate
-
unactivated mutant enzyme W181S, at pH 7.4, temperature not specified in the publication
2.783
5-phospho-alpha-D-ribose 1-diphosphate
-
unactivated mutant enzyme W181Y, at pH 7.4, temperature not specified in the publication
3.668
5-phospho-alpha-D-ribose 1-diphosphate
-
unactivated mutant enzyme W181F, at pH 7.4, temperature not specified in the publication
0.533
9-(5-phospho-beta-D-ribosyl)xanthine
-
mutant E198D/E215D, in TM buffer
0.0059
diphosphate
-
mutant E198D/E215D, in the presence of 1 mM 9-(5-phospho-beta-D-ribosyl)xanthine
0.028
diphosphate
-
mutant E215Q, in the presence of 1 mM 9-(5-phospho-beta-D-ribosyl)xanthine
0.039
diphosphate
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wild-type, in the presence of 1 mM 9-(5-phospho-beta-D-ribosyl)xanthine
0.115
diphosphate
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mutant E215D, in the presence of 1 mM 9-(5-phospho-beta-D-ribosyl)xanthine
0.133
diphosphate
-
mutant E198D, in the presence of 1 mM 9-(5-phospho-beta-D-ribosyl)xanthine
0.0049
guanine
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mutant E198D/E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.025
guanine
-
mutant E215Q, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.1
guanine
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mutant E198D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.1
guanine
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mutant E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.0021
hypoxanthine
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mutant E198D/E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.091
hypoxanthine
pH and temperature not specified in the publication
0.129
hypoxanthine
-
mutant E215Q, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.458
hypoxanthine
-
wild-type, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.524
hypoxanthine
-
mutant E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.567
hypoxanthine
-
mutant E198D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.0073
xanthine
-
wild-type, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.0078
xanthine
-
mutant E198D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.0199
xanthine
-
mutant E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.035
xanthine
-
mutant E215Q, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
0.0913
xanthine
-
mutant E198D/E215D, at 25°C, 40 mM Tris-HCl, pH 7.5, 1 mM 5-phospho-alpha-D-ribose 1-diphosphate
