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2.4.2.4: thymidine phosphorylase

This is an abbreviated version!
For detailed information about thymidine phosphorylase, go to the full flat file.

Word Map on EC 2.4.2.4

Reaction

thymidine
+
phosphate
=
thymine
 +
2-deoxy-alpha-D-ribose 1-phosphate

Synonyms

angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase, animal growth regulators, blood platelet-derived endothelial cell growth factors, blood platelet-derived endothelial cell growth factor, deoA, deoxythymidine phosphorylase, dthdpase, EC 2.4.2.23, gliostatin, gliostatins, GLS, HTP, More, PD-ECGF, PD-ECGF/TP, PD-ECGF/TP platelet-derived endothelial cell growth factor, PDECGF, phosphorylase, thymidine, platelet derived endothelial cell growth factor, platelet derived endothelial cell grwoth factor, platelet derived-endothelial cell growth factor, platelet-derived endothelial cell growth factor, platelet-derived endothelial cell growth factor/thymidine phosphorylase, platelet-derived endotherial cell growth factor, ppnP, pynpase, pyrimidine deoxynucleoside phosphorylase, pyrimidine nucleoside phosphorylase, pyrimidine phosphorylase, pyrimidine/purine nucleoside phosphorylase, TDRPASE, ThdPase, thymidine phosphorylase, thymidine Pi deoxyribosyltransferase, thymidine-orthophosphate deoxyribosyltransferase, thymidine:orthophosphate deoxy-D-ribosyltransferase, Tpase, TYMP

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.4 thymidine phosphorylase

Cloned

Cloned on EC 2.4.2.4 - thymidine phosphorylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
co-expressed with uridine phosphorylase in Escherichia coli BL21(DE3) cells
-
expressed in Chinese hamster V-79 cells
-
expressed in CHO cells
-
expressed in Colo-320TP1 and C26A cells
-
expressed in Escherichia coli
-
expressed in Escherichia coli BL21(DE3) cells
expressed in Escherichia coli Rosetta (DE3) cells
expressed in Jurkat cells
-
expressed in V-79 hamster cells
-
expressed in V79 Chinese hamster cells
-
expression in KB cells
expression in rat vascular smooth muscle cell
-
expression of the calmodulin binding protein-tagged enzyme in Escherichia coli strain BL21(DE3) cells transformed with the pCal-n-EK/TP and pGroESL vectors
-
expression of wild-type and mutan enzymes in Escherichia coli strain BL21(DE3)
recombinant enzyme lacks 10 amino acids at amino-terminus
-
transfected into colon cancer cell line Colo320
-