2.4.2.43: lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase

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For detailed information about lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase, go to the full flat file.

Reaction

Synonyms

4-amino-4-deoxy-L-arabinose transferase, aminoarabinose transferase, arnT, L-Ara4N transferase, undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.43 lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase

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Results	in table
1	Activating Compound
3939	AA Sequence
5	Cloned(Commentary)
1	Crystallization (Commentary)
2	Expression
3	General Information
2	Inhibitors
10	Localization
1	Metals/Ions
5	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
18	Organism
2	Pathway
1	PDB ID
3	pH Optimum
12	Protein Variants
3	Purification (Commentary)
4	Reaction
14	Reference
19	Substrates and Products (Substrate)
7	Subunits
21	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 2.4.2.43 - lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase

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SYSTEMATIC NAME

IUBMB Comments

4-amino-4-deoxy-alpha-L-2-aminoarabinopyranosyl ditrans,octacis-undecaprenyl phosphate:lipid IVA L-2-aminoarabinopyranosyltransferase

Integral membrane protein present in the inner membrane of certain Gram negative endobacteria. In strains that do not produce 3-deoxy-D-manno-octulosonic acid (Kdo), the enzyme adds a single arabinose unit to the 1-phosphate moiety of the tetra-acylated lipid A precursor, lipid IVA. In the presence of a Kdo disaccharide, the enzyme primarily adds an arabinose unit to the 4-phosphate of lipid A molecules. The Salmonella typhimurium enzyme can add arabinose units to both positions.