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2.4.2.6: nucleoside deoxyribosyltransferase

This is an abbreviated version!
For detailed information about nucleoside deoxyribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.6

Reaction

2-deoxy-D-ribosyl-base1
+
base2
=
2-deoxy-D-ribosyl-base2
+
base1

Synonyms

2'-deoxyribosyltransferase, 2'-N-deoxyribosyltransferase, Chro_1188, CtNDT, deoxynucleoside 5-monophosphate N-glycosidase, deoxyribose transferase, deoxyribosyltransferase, nucleoside, DRTase I, DRTase II, GQR93_14380, LaNDT, LhNDT, LlNDT, LmPDT, LrNDT, N-deoxyribosyltransferase, N-deoxyribosyltransferase II, NDRT, NdRT-II, NDT, NDT-II, NDT4, NTD, nucleoside 2'-deoxyribosyltransferase, nucleoside 2'-deoxyribosyltransferase type II, nucleoside 2-deoxyribosyltransferase, nucleoside deoxyribosyltransferase I, nucleoside deoxyribosyltransferase II, nucleoside N-deoxyribosyltransferase, nucleoside trans-N-deoxyribosylase, PDT, purine nucleoside 2'-deoxyribosyltransferase, purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl transferase, RCL, Tb927.5.1360, TbPDT, trans-deoxyribosylase, trans-N-deoxyribosylase, trans-N-glycosidase, transdeoxyribosylase, type I NDT, YejD

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.6 nucleoside deoxyribosyltransferase

Specific Activity

Specific Activity on EC 2.4.2.6 - nucleoside deoxyribosyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.017
wild-type, with 2',3'-dideoxythymidine and adenine as substrates
0.02
mutant G9S, with 2'-deoxyinosine and adenine as substrates
0.036
0.056
wild-type, with 2',3'-dideoxyuridine and cytosine as substrates
0.13
purified recombinant wild-type enzyme, pH 6.0, 37°C, substrate 2',3'-dideoxyinosine
0.19
wild-type, with 2',3'-dideoxyuridine and cytosine as substrates
0.25
mutant G9S, with 3'-dideoxythymidine and adenine as substrates
0.4
mutant G9S, with 2',3'-dideoxyguanosine and thymine as substrates
0.42
mutant A15T, 2',3'-dideoxyadenosine and thymine as substrates
0.46
mutant A15T, 2'-deoxyadenosine and thymine as substrates
0.47
mutant G9S, with 2'-deoxyinosine and adenine as substrates
0.57
mutant G9S, with 2'-deoxyguanosine and thymine
0.6
mutant G9S, with 2',3'-dideoxyguanosine and thymine as substrates
0.86
purified recombinant mutant NDT G10S, pH 6.0, 37°C, substrate 2',3'-dideoxyinosine
0.9
recombinant wild-type enzyme with substrates inosine and adenine, pH 6.0, 50°C
1.04
mutant G9S, with 2'-deoxythymidine and adenine as substrates
1.08
wild-type, with 2'-deoxyinosine and adenine as substrates
1.25
mutant G9S, with 2'-deoxycytidine and hypoxanthine as substrates
1.3
mutant G9S, with 2',3'-dideoxyuridine and cytosine as substrates
1.35
mutant A15T, 2',3'-dideoxyadenosine and cytosine as substrates
1.47
mutant A15T, 2',3'-dideoxycytidine and thymine as substrates
10.5
purified recombinant wild-type enzyme, pH 6.0, 50°C, substrates 2'-deoxyadenosine and guanine
11.1
recombinant mutant Y5F/N53D with substrates 2'-deoxyinosine and adenine, pH 4.0, 50°C
11.3
recombinant mutant Y5F with substrates 2'-deoxyinosine and adenine, pH 6.0, 50°C
11.9
wild-type, with 2'-deoxythymidine and adenine as substrates
12.3
recombinant mutant Y5F with substrates 2'-deoxyinosine and adenine, pH 4.0, 50°C
12.7
mutant G9S, with 2'-deoxyuridine and cytosine as substrates
173
wild-type, with 2'-deoxycytidine and adenine as substrates
2.7
recombinant mutant Y5F with substrates inosine and adenine, pH 6.0, 50°C
21.4
purified recombinant wild-type enzyme, pH 6.0, 50°C, substrates 2'-deoxyguanosine and adenine
27.1
mutant G9S, with 2'-deoxycytidine and adenine as substrates
29
wild-type, with 2',3'-dideoxycytidine and adenine as substrates
3.1
mutant G9S, with 2'-deoxyuridine and cytosine as substrates
3.6
wild-type, with 2'-deoxyinosine and adenine as substrates
32
wild-type, 2'-deoxycytidine and thymine as substrates
33.2
wild-type, 2'-deoxyadenosine and cytosine as substrates
36.8
-
DRTase II, reaction with thymidine + adenine
39
purified recombinant wild-type enzyme, pH 6.0, 50°C, substrates 2'-deoxyguanosine and hypoxanthine
4.95
wild-type, with 2'-deoxyguanosine and thymine
40.2
wild-type, with 2'-deoxyuridine and cytosine as substrates
42.5
wild-type, with 2'-deoxyuridine and cytosine as substrates
42.9
-
DRTase I, reaction with deoxyinosine and adenine
43
-
reaction with deoxycytidine and adenine
5.2
wild-type, with 2'-deoxyguanosine and thymine
50.3
purified recombinant mutant V11A, pH 6.0, 50°C, substrates 2'-deoxyguanosine and adenine
59.9
purified recombinant mutant V11S, pH 6.0, 50°C, substrates 2'-deoxyguanosine and adenine
6
mutant G9S, with 2',3'-dideoxycytidine and adenine as substrates
6.67
-
equals 100%, purified protein, in presence of 0.5 mg/ml bovine serum albumin, pH 7.5, 10 min, 25°C
7.11
mutant A15T, 2'-deoxycytidine and thymine as substrates
7.3
recombinant mutant Y5F/N53D with substrates 2'-deoxyinosine and adenine, pH 6.0, 50°C
7.75
-
reaction with thymidine and cytosine
8.4
wild-type, 2'-deoxyadenosine and thymine as substrates
84.7
purified recombinant mutant V11A, pH 6.0, 50°C, substrates 2'-deoxyinosine and adenine
9.5
purified recombinant wild-type enzyme, pH 6.0, 50°C, substrates 2'-deoxyadenosine and hypoxanthine
90.7
purified recombinant mutant V11S, pH 6.0, 50°C, substrates 2'-deoxyinosine and adenine
additional information