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2.4.2.7: adenine phosphoribosyltransferase

This is an abbreviated version!
For detailed information about adenine phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.7

Reaction

AMP
+
diphosphate
=
adenine
+
5-phospho-alpha-D-ribose 1-diphosphate

Synonyms

adenine phosphoribosyl transferase, adenine phosphoribosylpyrophosphate transferase, adenine phosphoribosyltransferase, adenine phosphoribosyltransferase 2, adenione PRTase, adenosine phosphoribosyltransferase, adenylate pyrophosphorylase, adenylic pyrophosphorylase, AMP pyrophosphorylase, AMP-pyrophosphate phosphoribosyltransferase, AMP:pyrophosphate phospho-D-ribosyltransferase, APRT, APRT1, APRT2, APRTase, APRTh, apT, APT1, APT2, APT4, APT5, ApTR, FtAPRT, gpT-1, hAPRT, More, phosphoribosyltransferase, adenine, ScAPRT, SmAPRT1, Smp_054360, SSO2342, transphosphoribosidase, TtAPRT2, TTC1249, TTC1250, TTH1250, TTHA1614, TthAPRT, TthHB27APRT, TT_C1249, TT_C1250, type I PRT

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.7 adenine phosphoribosyltransferase

Specific Activity

Specific Activity on EC 2.4.2.7 - adenine phosphoribosyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00000004
-
-
0.0004 - 0.0006
-
wild-type erythrocytes
0.00086
-
HPRT F199C mutant erythrocytes
0.0056
recombinant mutant F23A enzyme, pH 7.5, 30-34°C
0.0073
-
wild-type MN9D cells
0.156
-
purified enzyme
0.32
purified recombinant enzyme, pH 8.5, 70°C, substrate adenine
1.1
-
purified enzyme
1.15
recombinant wild-type enzyme, pH 7.5, 30-34°C
103
substrate 6-methoxyguanine, pH 8.0, 70°C, recombinant enzyme
14.2
-
purified enzyme
1430
-
crude cell extract, pH 7.5, temperature not specified in the publication
15.14
-
purified enzyme
2.2
-
purified enzyme
20.6
-
purified enzyme
2050
-
crude cell extract, pH 7.5, temperature not specified in the publication
21.8
-
purified enzyme
300
-
purified enzyme, pH 8.8, 37°C
405
substrate 2-chloroadenine, pH 8.0, 70°C, recombinant enzyme
641
substrate 2,6-diaminopurine, pH 8.0, 70°C, recombinant enzyme
785
substrate 2-fluoroadenine, pH 8.0, 70°C, recombinant enzyme
9.58
-
purified enzyme
90
substrate 6-methylpurine, pH 8.0, 70°C, recombinant enzyme
additional information