2.4.2.7: adenine phosphoribosyltransferase
This is an abbreviated version!
For detailed information about adenine phosphoribosyltransferase, go to the full flat file.
Word Map on EC 2.4.2.7
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2.4.2.7
-
purine
-
hamster
-
hypoxanthine
-
salvage
-
2,8-dihydroxyadenine
-
ovary
-
erythrocyte
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hypoxanthine-guanine
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nucleoside
-
stone
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guanine
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urolithiasis
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allopurinol
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deaminase
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xanthine
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hgprt
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heterozygosity
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inosine
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uric
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lesch-nyhan
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nephrolithiasis
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hemizygous
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2,6-diaminopurine
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phosphoribosyltransferases
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imp
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5-phosphoribosyl-1-pyrophosphate
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gout
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radiolucent
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calculi
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transversions
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crystalluria
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hprt-deficient
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repair-deficient
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lithiasis
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hgprtase
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synthesis
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drug development
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hemolysates
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3.5.4.4
-
repair-proficient
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2.7.1.20
-
medicine
- 2.4.2.7
- purine
- hamster
- hypoxanthine
-
salvage
-
2,8-dihydroxyadenine
- ovary
- erythrocyte
-
hypoxanthine-guanine
- nucleoside
- stone
- guanine
- urolithiasis
- allopurinol
- deaminase
- xanthine
- hgprt
-
heterozygosity
- inosine
-
uric
- lesch-nyhan
- nephrolithiasis
-
hemizygous
- 2,6-diaminopurine
- phosphoribosyltransferases
- imp
-
5-phosphoribosyl-1-pyrophosphate
- gout
-
radiolucent
- calculi
-
transversions
-
crystalluria
-
hprt-deficient
-
repair-deficient
- lithiasis
- hgprtase
- synthesis
- drug development
-
hemolysates
-
3.5.4.4
-
repair-proficient
-
2.7.1.20
- medicine
Reaction
Synonyms
adenine phosphoribosyl transferase, adenine phosphoribosylpyrophosphate transferase, adenine phosphoribosyltransferase, adenine phosphoribosyltransferase 2, adenione PRTase, adenosine phosphoribosyltransferase, adenylate pyrophosphorylase, adenylic pyrophosphorylase, AMP pyrophosphorylase, AMP-pyrophosphate phosphoribosyltransferase, AMP:pyrophosphate phospho-D-ribosyltransferase, APRT, APRT1, APRT2, APRTase, APRTh, apT, APT1, APT2, APT4, APT5, ApTR, FtAPRT, gpT-1, hAPRT, More, phosphoribosyltransferase, adenine, ScAPRT, SmAPRT1, Smp_054360, SSO2342, transphosphoribosidase, TtAPRT2, TTC1249, TTC1250, TTH1250, TTHA1614, TthAPRT, TthHB27APRT, TT_C1249, TT_C1250, type I PRT
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2.4.2.7 adenine phosphoribosyltransferaseAdvanced search results
results (
results (Temperature Stability
Temperature Stability on EC 2.4.2.7 - adenine phosphoribosyltransferase
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TEMPERATURE STABILITY 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
0
-
in absence of Mg2+ and donor substrate, loss of 50% activity after 18 min
37
-
in absence of Mg2+ and donor substrate, loss of 97% activity after 10 min
50
60
70
80
additional information
50
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40 min, 5 mM MgCl2, more than 90% loss of activity, + 0.4 mM 5-phospho-alpha-D-ribose 1-diphosphate, 30% loss of activity
70
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complete inactivation of Propositus (HPRT-) after 20 min, complete inactivation of control(HPRT+) after 10 min
80
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complete inactivation of Propositus (HPRT-) after 13 min, complete inactivation of control(HPRT+) after 7 min
additional information
compared with the substrate-free form, the unfolding temperature of the 5-phospho-alpha-D-ribose 1-diphosphate (PRPP)-bound enzyme is increased by 30°C, which suggests that PRPP protects the enzyme from thermodenaturation
additional information
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compared with the substrate-free form, the unfolding temperature of the 5-phospho-alpha-D-ribose 1-diphosphate (PRPP)-bound enzyme is increased by 30°C, which suggests that PRPP protects the enzyme from thermodenaturation
additional information
the immobilization process improved the thermostability of TtAPRT2
