2.4.2.9: uracil phosphoribosyltransferase

This is an abbreviated version!
For detailed information about uracil phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

AFR052C, AFR052Cp, AGOS_AFR052C, AgUPRT, CD-UPRT, cytosine deaminase-uracil phosphoribosyltransferase, cytosine deaminase/uracil phosphoribosyltransferase, More, MtUPRT, phosphoribosyltransferase, uracil, Rv3309c, TtUPRT, TtUPRT3, UK/UPRT1, UMP pyrophosphorylase, UMP:pyrophosphate phosphoribosyltransferase, UPP, UPRT, UPRTase, uracil phosphoribosyl transferase, uridine 5'-phosphate pyrophosphorylase, uridine kinase-like protein (uracil phosphoribosyltransferase), uridine kinase/uracil phosphoribosyltransferase 1, uridine monophosphate pyrophosphorylase, uridylate pyrophosphorylase, uridylic pyrophosphorylase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.9 uracil phosphoribosyltransferase

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Results	in table
22	Activating Compound
44618	AA Sequence
15	Application
1	CAS Registry Number
34	Cloned(Commentary)
7	Crystallization (Commentary)
312	Disease/ Diagnostics
24	General Information
10	General Stability
1	IC50 Value
49	Inhibitors
5	Ki Value [mM]
46	KM Value [mM]
4	Localization
43	Metals/Ions
33	Molecular Weight [Da]
32	Natural Substrates/ Products (Substrates)
368	Organism
5	Pathway
104	PDB ID
21	pH Optimum
7	pH Range
2	pI Value
20	Protein Variants
21	Purification (Commentary)
10	Reaction
1	Reaction Type
66	Reference
30	Source Tissue
19	Specific Activity [micromol/min/mg]
12	Storage Stability
109	Substrates and Products (Substrate)
36	Subunits
88	Synonyms
1	Systematic Name
16	Temperature Optimum [°C]
2	Temperature Range [°C]
14	Temperature Stability [°C]
8	Turnover Number [1/s]

KI Value

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KI Value on EC 2.4.2.9 - uracil phosphoribosyltransferase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.025

5-fluorouracil

Toxoplasma gondii

-

-

638367

0.24

diphosphate

Giardia intestinalis

-

competitive versus 5-phosphoribose 1-diphosphate

638368

0.017

tetrahydrouridine

Giardia intestinalis

-

-

638368

0.015

UMP

Giardia intestinalis

-

competitive versus uracil

638368

additional information

additional information

Bacillus subtilis

-

product inhibition pattern

638371

-