2.4.99.17: S-adenosylmethionine:tRNA ribosyltransferase-isomerase
This is an abbreviated version!
For detailed information about S-adenosylmethionine:tRNA ribosyltransferase-isomerase, go to the full flat file.
Word Map on EC 2.4.99.17
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2.4.99.17
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nucleoside
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hypermodified
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penultimate
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7-aminomethyl-7-deazaguanine
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thermotoga
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anticodon
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maritima
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compelling
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isomerization
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trna-modifying
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trnatyr
- 2.4.99.17
- nucleoside
-
hypermodified
-
penultimate
- 7-aminomethyl-7-deazaguanine
-
thermotoga
-
anticodon
- maritima
-
compelling
-
isomerization
-
trna-modifying
- trnatyr
Reaction
Synonyms
QueA, QueA enzyme, queuosine biosynthesis protein, queuosine biosynthesis protein QueA, S-adenosylmethionine:tRNA ribosyltransferase-isomerase, TM0574
ECTree
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Systematic Name
Systematic Name on EC 2.4.99.17 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase
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S-adenosyl-L-methionine:7-aminomethyl-7-deazaguanosine ribosyltransferase (ribosyl isomerizing; L-methionine, adenine releasing)
The reaction is a combined transfer and isomerization of the ribose moiety of S-adenosyl-L-methionine to the modified guanosine base in the wobble position in tRNAs specific for Tyr, His, Asp or Asn. It is part of the queuosine biosynthesis pathway.