2.4.99.18: dolichyl-diphosphooligosaccharide-protein glycotransferase

This is an abbreviated version!
For detailed information about dolichyl-diphosphooligosaccharide-protein glycotransferase, go to the full flat file.

Word Map on EC 2.4.99.18

2.4.99.18

n-glycosylation

n-linked

glycans

lipid-linked

sequons

asparagine-linked

jejuni

campylobacter

dolichol

ribophorins

otase

cotranslational

bloc

dolichol-linked

translocon

glc3man9glcnac2

heptasaccharide

s-layer

underglycosylation

preassembled

mannosyltransferases

glycoengineering

hypoglycosylation

hetero-oligomeric

single-subunit

translocon-associated

man9glcnac2

lari

drug development

biotechnology

medicine

n-glycoproteins

glycoproteomics

pilins

Reaction

a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine

Synonyms

AglB, AglB-L, AlgB, asparagine N-glycosyltransferase, DGL1, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2, dolichyl-diphosphooligosaccharide-protein glycosyltransferase, dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase, EC 2.4.1.119, glycosyltransferase, dolichyldiphosphooligosaccharide-protein, glycosyltransferase, dolichylpyrophosphodiacetylchitobiose-protein, L.m.STT3, Lm STT3, oligomannosyltransferase, oligosaccharide transferase, oligosaccharyl transferase, oligosaccharyl transferase 16 kDa subunit, oligosaccharyl transferase subunit epsilon, oligosaccharyl transferase subunit OST2, oligosaccharyltransferase, oligosaccharyltransferase complex, oligosaccharyltransferase STT3, oligosaccharyltransferase, dolichyldiphosphoryloligosaccharide-protein, OST, OST-A, OST-B, OST-I, OST-II, OST-III, OST1, OST2, OST3, Ost3p, OST4, OST5, Ost6p, OSTC(I), OSTC(II), OSTC(III), OTase, PglB, PglB oligosaccharyltransferase, PglB1, PglL, PilO, STT3, STT3 protein, STT3-1, STT3-2, STT3-3, STT3-4, Swp1p, TbSTT3A, TbSTT3B, TbSTT3C, Wbp1p, yeast oligosaccharyl transferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.99 Transferring other glycosyl groups

2.4.99.18 dolichyl-diphosphooligosaccharide-protein glycotransferase

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Results	in table
3	Activating Compound
7433	AA Sequence
7	Application
1	CAS Registry Number
33	Cloned(Commentary)
9	Crystallization (Commentary)
57	Disease/ Diagnostics
1	Expression
34	General Information
5	General Stability
29	Inhibitors
38	KM Value [mM]
66	Localization
15	Metals/Ions
38	Molecular Weight [Da]
64	Natural Substrates/ Products (Substrates)
211	Organism
4	Pathway
31	PDB ID
8	pH Optimum
1	pH Range
4	Posttranslational Modification
90	Protein Variants
23	Purification (Commentary)
1	Reaction
1	Reaction Type
178	Reference
41	Source Tissue
4	Specific Activity [micromol/min/mg]
4	Storage Stability
224	Substrates and Products (Substrate)
48	Subunits
284	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
6	Temperature Stability [°C]

Organism

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Organism on EC 2.4.99.18 - dolichyl-diphosphooligosaccharide-protein glycotransferase

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Arabidopsis thaliana

2 entries

Archaeoglobus fulgidus

3 entries

Archaeoglobus fulgidus DSM 4306

NBRC 100126, three AglB paralogues

UniProt

calf

Caldivirga maquilingensis

UniProt

Candidatus Korarchaeum cryptofilum

708519

B1L5S3

UniProt

Canis lupus familiaris

488495, 488501, 488509, 488513, 658122, 659919, 673879, 720164

Crithidia fasciculata

488498

Cryptococcus neoformans

675004

Desulfurococcus amylolyticus

708519

B8D352

UniProt

Drosophila melanogaster

488495

Entamoeba histolytica

675004

Gallus gallus

2 entries

Haloarcula marismortui

2 entries

Halobacterium salinarum

2 entries

Halobacterium salinarum NRC-1

708519

Q9HQP2

UniProt

Haloferax mediterranei

726749

Haloferax volcanii

676071, 689058, 726749

Haloferax volcanii DSM 3757

726749

Haloquadratum walsbyi

708519

Q18GV3

UniProt

Halorubrum lacusprofundi

708519

B9LMS1

UniProt

Helicobacter pullorum

UniProt

Hyperthermus butylicus

708519

A2BM28

UniProt

Ignicoccus hospitalis

UniProt

Metallosphaera sedula

708519

A4YHQ7

UniProt

Methanobrevibacter smithii

708519

A5UL43

UniProt

Methanocaldococcus jannaschii

708519

Q58920

UniProt

Methanocella arvoryzae MRE50

708519

Q0W803, Q0W817, Q0W818

UniProt

Methanococcoides burtonii

708519

Q12VP3

UniProt

Methanococcus aeolicus

708519

A6UWW3

UniProt

Methanococcus maripaludis C5

708519

A4FWA0

UniProt

Methanococcus maripaludis C6

708519

A9A9N9

UniProt

Methanococcus maripaludis C7

708519

A6VH10

UniProt

Methanococcus maripaludis S2

708519

Q6LXC8

UniProt

Methanococcus vannielii

UniProt

Methanocorpusculum labreanum

708519

A2SR78

UniProt

Methanoculleus marisnigri

UniProt

UniProt

Methanosarcina acetivorans

708519

Q8TJM6, Q8TJM7, Q8TJM8, Q8TRK3

UniProt

Methanosarcina barkeri

708519

Q46FJ0, Q46FW5, Q46FW6

UniProt

Methanosarcina mazei

708519

Q8PUW8, Q8PZ47, Q8PZ48

UniProt

Methanosphaera stadtmanae

708519

Q2NHD2

UniProt

Methanosphaerula palustris

708519

B8GG73

UniProt

Methanospirillum hungatei

708519

Q2FSJ2, Q2FTM5, Q2FUP2

UniProt

Methanothermobacter thermautotrophicus str. Delta H

708519

O27660

UniProt

Methanothrix thermoacetophila

UniProt

Nanoarchaeum equitans

708519

Q74MN3

UniProt

Natronomonas pharaonis

708519

Q3IPK0

UniProt

Neisseria meningitidis

2 entries

Nitrosopumilus maritimus

708519

A9A114

UniProt

no activity in Aeropyrum pernix

708519

no activity in Methanopyrus kandleri

708519

Oryctolagus cuniculus

UniProt

Pseudomonas aeruginosa

687397

Pyrobaculum aerophilum

708519

Q8ZTY7

UniProt

Pyrobaculum arsenaticum

708519

A4WLR5

UniProt

Pyrobaculum calidifontis

708519

A3MUV5

UniProt

Pyrobaculum islandicum

708519

A1RRM7

UniProt

Pyrobaculum neutrophilum

UniProt

Q9UYP5, Q9UZF5, Q9V250

UniProt

Pyrococcus furiosus

4 entries

Pyrococcus horikoshii

708519

O58981, O74088

UniProt

Rattus norvegicus

488495, 488497, 488498

Saccharolobus solfataricus

708519

Q97Z77

UniProt

Saccharomyces cerevisiae

26 entries

Saccharomyces cerevisiae ATCC 204508

P41543: dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 1, P46964: dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 2, P48439: dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 3, Q99380: dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 4, Q92316: dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 5, P39007: dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit STT3 (catalytic subunit), P33767: dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit WBP1, Q02795: dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit SWP1

758885

P41543; P46964; P48439; Q99380; Q92316; P39007; P33767; Q02795

SwissProt

Saccharomyces cerevisiae LY510-514

690092

Staphylothermus marinus

UniProt

Sulfolobus acidocaldarius

708519

Q4J9B4

UniProt

Sulfurisphaera tokodaii

708519

Q973G2

UniProt

Sus scrofa

488502, 488506, 488512, 488513, 488514

Thermococcus kodakarensis

syn. Pyrococcus kodakaraensis

708519

Q5JH70, Q5JJ26

UniProt

Thermococcus onnurineus

UniProt

UniProt

Thermoplasma acidophilum

708519

Q9HJ37

UniProt

Thermoplasma volcanium

708519

Q979C6

UniProt

Trichomonas vaginalis