2.5.1.112: adenylate dimethylallyltransferase (ADP/ATP-dependent)
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For detailed information about adenylate dimethylallyltransferase (ADP/ATP-dependent), go to the full flat file.
Reaction
Synonyms
2-isopentenyl-diphosphate:ADP/ATP DELTA2-isopentenyltransferase, adenylate isopentenyltransferase, AIPT, ATP/ADP IPT, ATP/ADP isopentenyltransferase, cytokinin synthase, dimethylallyl diphosphate:ATP/ADP isopentenyltransferase, IPT, IPT1, IPT2, IPT3, IPT4, IPT5, IPT5a, IPT5b, IPT6, IPT7, IPT8, isopentenyl transferase 2, isopentenyltransferase
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General Information
General Information on EC 2.5.1.112 - adenylate dimethylallyltransferase (ADP/ATP-dependent)
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malfunction
the ipt1357 quadruple mutant possesses severely decreased levels of isopentenyladenine and trans-zeatin , and their corresponding ribosides, ribotides, and glucosides, and is retarded in its growth. In contrast, these mutants possess increased levels of cis-zeatin-type cytokinins
metabolism
physiological function
the enzyme isoforms are responsible for the bulk of isopentenyladenine- and trans-zeatin-type cytokinin synthesis
metabolism
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the isopentenyltransferase reaction is the key rate-limiting step in cytokinin biosynthesis
physiological function
interference of auxin distribution disrupts the cytokinin response and ATP/ADP isopentenyltransferase IPT5 expression, affecting stem cell initiation and meristem formation. Auxin response factor ARF3 mediates the auxin response during de novo organ regeneration. Mutations in ARF3 cause ectopic cytokinin biosynthesis via the misexpression of IPT5, and this disrupts organ regeneration. ARF3 directly binds to the promoter of IPT5 and negatively regulates IPT5 expression
physiological function
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enzyme genes in nodal stems are key genes for cytokinin biosynthesis, as they promote the outgrowth of axillary buds
physiological function
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isoform IPT5 in seed is the key gene for cytokinin biosynthesis during early fruit development. Isoform IPT3 is the primary nitrate-response gene in peach roots