2.5.1.112: adenylate dimethylallyltransferase (ADP/ATP-dependent)

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For detailed information about adenylate dimethylallyltransferase (ADP/ATP-dependent), go to the full flat file.

Reaction

Synonyms

2-isopentenyl-diphosphate:ADP/ATP DELTA2-isopentenyltransferase, adenylate isopentenyltransferase, AIPT, ATP/ADP IPT, ATP/ADP isopentenyltransferase, cytokinin synthase, dimethylallyl diphosphate:ATP/ADP isopentenyltransferase, IPT, IPT1, IPT2, IPT3, IPT4, IPT5, IPT5a, IPT5b, IPT6, IPT7, IPT8, isopentenyl transferase 2, isopentenyltransferase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.112 adenylate dimethylallyltransferase (ADP/ATP-dependent)

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Results	in table
16	AA Sequence
7	Cloned(Commentary)
17	Cofactor
1	Crystallization (Commentary)
12	Expression
7	General Information
6	kcat/KM [mM/s]
10	KM Value [mM]
2	Metals/Ions
3	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
24	Organism
6	Pathway
1	pH Optimum
11	Protein Variants
5	Purification (Commentary)
2	Reaction
12	Reference
35	Source Tissue
47	Substrates and Products (Substrate)
3	Subunits
83	Synonyms
1	Systematic Name
6	Turnover Number [1/s]

General Information

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General Information on EC 2.5.1.112 - adenylate dimethylallyltransferase (ADP/ATP-dependent)

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

malfunction

Arabidopsis thaliana

Q93WC9, Q94ID1, Q94ID2, Q94ID3, Q9C6L1, Q9LJL4, Q9SB60

the ipt1357 quadruple mutant possesses severely decreased levels of isopentenyladenine and trans-zeatin , and their corresponding ribosides, ribotides, and glucosides, and is retarded in its growth. In contrast, these mutants possess increased levels of cis-zeatin-type cytokinins

676830

metabolism

2 entries

physiological function

4 entries

metabolism

Arabidopsis thaliana

Q93WC9, Q94ID1, Q94ID2, Q94ID3, Q9C6L1, Q9LJL4, Q9SB60

the enzyme isoforms are responsible for the bulk of isopentenyladenine- and trans-zeatin-type cytokinin synthesis

676830

metabolism

Humulus lupulus

-

the isopentenyltransferase reaction is the key rate-limiting step in cytokinin biosynthesis

722266

physiological function

Zea mays

-

the enzyme is expressed during kernel development

689564

physiological function

Arabidopsis thaliana

Q94ID2

interference of auxin distribution disrupts the cytokinin response and ATP/ADP isopentenyltransferase IPT5 expression, affecting stem cell initiation and meristem formation. Auxin response factor ARF3 mediates the auxin response during de novo organ regeneration. Mutations in ARF3 cause ectopic cytokinin biosynthesis via the misexpression of IPT5, and this disrupts organ regeneration. ARF3 directly binds to the promoter of IPT5 and negatively regulates IPT5 expression

739343

physiological function

Prunus persica

-

enzyme genes in nodal stems are key genes for cytokinin biosynthesis, as they promote the outgrowth of axillary buds

759943

physiological function

Prunus persica

-

isoform IPT5 in seed is the key gene for cytokinin biosynthesis during early fruit development. Isoform IPT3 is the primary nitrate-response gene in peach roots

759664