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2.5.1.115: homogentisate phytyltransferase

This is an abbreviated version!
For detailed information about homogentisate phytyltransferase, go to the full flat file.

Word Map on EC 2.5.1.115

Reaction

phytyl diphosphate
+
homogentisate
=
diphosphate
+
2-methyl-6-phytylbenzene-1,4-diol
+
CO2

Synonyms

At2g18950, HPT, HPT1, RTD1, slr1736, SynHPT, VTE2, VTE2-1, VTE2-2, VTE2.1

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.115 homogentisate phytyltransferase

Expression

Expression on EC 2.5.1.115 - homogentisate phytyltransferase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
abiotic stress results in an 18 and 8fold increase in total tocopherol content in wild-type and isoform HPT1 overexpressing leaves, respectively, with tocopherol levels in the ovrexpressing strain being 2- to 4fold higher than wild type at all experimental time points. Increased total tocopherol levels correlate with elevated HPT mRNA levels and HPT specific activity
enzyme is constitutively expressed in all analyzed tissues except in kernel 15 weeks after anthesis. Enzyme is highly expressed at the fruit ripening stage of 17 weeks after anthesis
isoform Hpt1 is strongly regulated by dark and low-temperature. Under the same treatments, alpha-tocopherol increases in cultures exposed to darkness or heat, whereas gamma-tocopherol does it in low temperature
the expression patterns of the five tocopherol biosynthetic genes vary in different plant tissues and under different stress conditions. All five genes are highly expressed in leaf tissues, whereas 4-hydroxyphenylpyruvate dioxygenase and homogentisate phytyltransferase are highly expressed in the thick roots. The expression patterns of these five genes significantly differ in response to PEG, NaCl and H2O2-mediated oxidative stress. Homogentisate phytyltransferase is strongly induced following PEG treatment