2.5.1.118: beta-(isoxazolin-5-on-2-yl)-L-alanine synthase

This is an abbreviated version!
For detailed information about beta-(isoxazolin-5-on-2-yl)-L-alanine synthase, go to the full flat file.

Reaction

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.118 beta-(isoxazolin-5-on-2-yl)-L-alanine synthase

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2	KM Value [mM]
2	Natural Substrates/ Products (Substrates)
2	Organism
1	Pathway
2	pH Optimum
2	Purification (Commentary)
1	Reaction
2	Reference
4	Source Tissue
4	Substrates and Products (Substrate)
1	Systematic Name

Substrates Products

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Substrates Products on EC 2.5.1.118 - beta-(isoxazolin-5-on-2-yl)-L-alanine synthase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

O3-acetyl-L-serine + isoxazolin-5-one

3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate

4 entries

O3-acetyl-L-serine + isoxazolin-5-one

3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate

Lathyrus odoratus

-

the enzyme also forms 3-(5-oxoisoxazolin-4-yl)-L-alanine in vitro (cf. EC 2.5.1.119). Only 3-(5-oxoisoxazolin-2-yl)-L-alanine is formed in vivo. 3-(5-oxoisoxazolin-2-yl)-L-alanine is the biosynthetic precursor of the neurotoxin N3-oxalyl-L-2,3-diaminopropanoic acid, the cause of lathyrism

637377

-

-

?

O3-acetyl-L-serine + isoxazolin-5-one

3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate

Lathyrus odoratus

-

the enzyme also forms 3-(5-oxoisoxazolin-4-yl)-L-alanine in vitro (cf. EC 2.5.1.119). Only 3-(5-oxoisoxazolin-2-yl)-L-alanine is formed in vivo

637377

-

-

?

O3-acetyl-L-serine + isoxazolin-5-one

3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate

Lathyrus sativus

-

the enzyme also forms 3-(5-oxoisoxazolin-4-yl)-L-alanine in vitro (cf. EC 2.5.1.119). Only 3-(5-oxoisoxazolin-2-yl)-L-alanine is formed in vivo. 3-(5-oxoisoxazolin-2-yl)-L-alanine is the biosynthetic precursor of the neurotoxin N3-oxalyl-L-2,3-diaminopropanoic acid, the cause of lathyrism

637377

-

-

?

O3-acetyl-L-serine + isoxazolin-5-one

3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate

Lathyrus sativus

-

the enzyme also forms 3-(5-oxoisoxazolin-4-yl)-L-alanine in vitro (cf. EC 2.5.1.119). Only 3-(5-oxoisoxazolin-2-yl)-L-alanine is formed in vivo

637377

-

-

?