2.5.1.16: spermidine synthase

This is an abbreviated version!
For detailed information about spermidine synthase, go to the full flat file.

Word Map on EC 2.5.1.16

2.5.1.16

polyamine

spermine

s-adenosylmethionine

ornithine

diamine

samdc

dicyclohexylamine

alpha-difluoromethylornithine

5'-methylthioadenosine

cadaverine

trypanothione

adometdc

agmatine

4.1.1.50

difluoromethylornithine

medicine

drug development

methylthioadenosine

thermospermine

nutrition

1,3-diaminopropane

biotechnology

norspermidine

multisubstrate

Reaction

S-adenosyl 3-(methylsulfanyl)propylamine

Synonyms

aminopropyltransferase, aminopropyltransferase spermidine synthase, AtSPDS1, AtSPDS2, MdSPDS1, PAPT, PgSPD, putrescine aminopropyltransferase, Spd synthase, SPDS, SPDS2, SPDSYN, spe-sdh, spe3, SpeE, spermidine synthase, spermidine synthase 1, spermidine synthetase, Spm synthase, SpSyn, Synpcc7942_0628, synthase, spermidine

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.16 spermidine synthase

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Results	in table
2	Activating Compound
21026	AA Sequence
5	Application
1	CAS Registry Number
40	Cloned(Commentary)
4	Cofactor
14	Crystallization (Commentary)
93	Disease/ Diagnostics
2	Expression
30	General Information
14	General Stability
10	IC50 Value
198	Inhibitors
6	kcat/KM [mM/s]
10	Ki Value [mM]
51	KM Value [mM]
6	Localization
13	Metals/Ions
53	Molecular Weight [Da]
73	Natural Substrates/ Products (Substrates)
650	Organism
7	Pathway
196	PDB ID
27	pH Optimum
5	pH Range
4	pH Stability
2	pI Value
24	Protein Variants
42	Purification (Commentary)
15	Reaction
1	Reaction Type
125	Reference
118	Source Tissue
18	Specific Activity [micromol/min/mg]
18	Storage Stability
206	Substrates and Products (Substrate)
41	Subunits
80	Synonyms
1	Systematic Name
37	Temperature Optimum [°C]
4	Temperature Range [°C]
8	Temperature Stability [°C]
22	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.5.1.16 - spermidine synthase

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S-adenosyl 3-(methylsulfanyl)propylamine + putrescine

S-methyl-5'-thioadenosine + spermidine

7 entries

S-adenosyl 3-(methylthio)propylamine + putrescine

S-methyl-5'-thioadenosine + spermidine

4 entries

S-adenosyl-3-methylthio-1-propylamine + 1,4-diaminobutane

5'-methylthioadenosine + spermidine

36 entries

S-adenosylmethioninamine + putrescine

5'-S-methyl-5'-thioadenosine + spermidine

8 entries

S-adenosylmethioninamine + putrescine

S-methyl-5'-thioadenosine + spermidine

8 entries

additional information

Arabidopsis thaliana

using yeast two-hybrid assays, spermidine synthase2 is identified as a specific 10A06 interactor. 10A06 is a cyst nematode (Heterodera glycines) secretory protein able to infect Arabidopsis thaliana, that is secreted as an effector into the developing syncytia during early plant parasitism

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