Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.5.1.17: corrinoid adenosyltransferase

This is an abbreviated version!
For detailed information about corrinoid adenosyltransferase, go to the full flat file.

Word Map on EC 2.5.1.17

Reaction

2 ATP + 2 cob(II)alamin +

a reduced flavoprotein
= 2 triphosphate + 2 adenosylcob(III)alamin +
an oxidized flavoprotein

Synonyms

ACAT, adenosyltransferase, vitamin B12s, aquacob(I)alamin adenosyltransferase, aquocob(I)alamin adenosyltransferase, ATP: cobalamin adenosyltransferase, ATP:co(I)rrinoid adenosyltransferase, ATP:cob(I)alamin adenosyltransferase, ATP:cob(I)alamin Cobeta-adenosyltransferase, ATP:cob(I)alamin transferase (ATR), ATP:Cob(I)alaminadenosyltransferase, ATP:cobalamin adenosyltransferase, ATP:cobalt(I) corrinoid adenosyltransferase, ATP:corrinoid adenosyltransferase, ATP:corrinoid adenosyltransferase PduO, ATR, cob(I)alamin adenosyltransferase, cob(I)yrinic acid a,c-diamide adenosyltransferase, CobA, CobA-type ATP:Co(I)rrinoid adenosyltransferase, cobalamin adenosyltransferase, CobAMm, cobO mutant SVQ336, cobO mutant SVQ524, cobO mutantSVQ336, EC 1.16.8.1, EutT, EutT adenosyltransferase, hATR, homologeous to PduO-type ATP: cob(I)alamin adenosyltransferase, human adenosyltransferase, human ATP: cob(I)alamin adenosyltransferase, human-type ACA, human-type ATP: co(I)rrinoid adenosyltransferase, human-type ATP: cob(I)alamin adenosyltransferase, LrPduO, methylmalonic aciduria type B, MMAB, MMAB protein, PduO, PduO adenosyltransferase, PduO enzyme, PduO protein, PduO-type ACA, PduO-type adenosine 5'-triphosphate:corrinoid adenosyltransferase, PduO-type ATP: cobalamin adenosyltransferase, PduO-type ATP:Co(I)rrinoid adenosyltransferase, PduO-type ATP:cob(I)alamin adenosyltransferase, PduO-type ATP:corrinoid adenosyltransferase, PduO-type corrinoid adenosyltransferase, ST1454, ST2180, TA1434, vitamin B12s adenosyltransferase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.17 corrinoid adenosyltransferase

Specific Activity

Specific Activity on EC 2.5.1.17 - corrinoid adenosyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.000125
0.0005
-
in presence of 1 mM ATP, 20 mM NADH, 2 mM FMN, 0.5 mM hydroxycobalamin and NAD(P)H: flavin oxidoreductase, 1.5 mM MgCl2, 100 mM KCl, pH 6
0.001
-
purified enzyme, pH 8.0
0.0061
0.02
-
purified recombinant enzyme
0.023
-
reductant: PduS protein, specific activity of LrPduO using different electron sources for the adenosylation of cob(II)alamin
0.026
-
reductant: PduS protein, specific activity of hATR using different electron sources for the adenosylation of cob(II)alamin
0.027
-
purified recombinant GST-tagged mutant R191W
0.034
recombinant mutant R124F
0.045
-
reductant: NADPH-dependent ferredoxin protein reductase, specific activity of LrPduO using different electron sources for the adenosylation of cob(II)alamin
0.047
0.053
0.061
0.072
-
reductant: NADPH-dependent ferredoxin protein reductase, specific activity of hATR using different electron sources for the adenosylation of cob(II)alamin
0.089
0.091
-
purified recombinant full length wild-type enzyme, in absence of Mg2+
0.098
0.143
-
purified recombinant wild-type enzyme
0.19
-
recombinant enzyme variant 239M
0.22
-
recombinant enzyme variant 239K
0.262
-
purified recombinant full length wild-type enzyme, in presence of 2.5 mM MgCl2
0.312
0.385
recombinant mutant R124A
0.49
-
reductant: Ti(III)citrate, specific activity of hATR using different electron sources for the adenosylation of cob(II)alamin
0.619
recombinant wild-type enzyme
additional information