2.5.1.21: squalene synthase
This is an abbreviated version!
For detailed information about squalene synthase, go to the full flat file.
Word Map on EC 2.5.1.21
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2.5.1.21
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farnesylation
-
cholesterol
-
prenylation
-
sterol
-
ftase
-
mevalonate
-
geranylgeranylation
-
isoprenoids
-
leukemia
-
geranylgeranyltransferase
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pyrophosphate
-
tipifarnib
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hmg-coa
-
statin
-
h-ras
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peptidomimetic
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epoxidase
-
prenyltransferase
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dolichols
-
rhob
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isoprenylation
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triterpene
-
farnesol
-
3-hydroxy-3-methylglutaryl
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lamins
-
ergosterol
-
cholesterol-lowering
-
hmgcr
-
prelamin
-
p21ras
-
lovastatin
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hutchinson-gilford
-
lanosterol
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manumycin
-
triterpenoids
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synthesis
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progerin
-
farnesylpyrophosphate
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cis-prenyltransferase
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drug development
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oxidosqualene
-
ras-transformed
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medicine
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ras-dependent
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nonsterols
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ras-mediated
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withanolides
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srebp-2
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ganoderic
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agriculture
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geranylgeraniol
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industry
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cycloartenol
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non-thiol
-
2,3-oxidosqualene
- 2.5.1.21
-
farnesylation
- cholesterol
-
prenylation
- sterol
- ftase
- mevalonate
-
geranylgeranylation
-
isoprenoids
- leukemia
-
geranylgeranyltransferase
- pyrophosphate
- tipifarnib
- hmg-coa
- statin
- h-ras
-
peptidomimetic
-
epoxidase
- prenyltransferase
- dolichols
- rhob
-
isoprenylation
-
triterpene
- farnesol
-
3-hydroxy-3-methylglutaryl
- lamins
- ergosterol
-
cholesterol-lowering
- hmgcr
-
prelamin
-
p21ras
- lovastatin
-
hutchinson-gilford
- lanosterol
- manumycin
-
triterpenoids
- synthesis
-
progerin
-
farnesylpyrophosphate
- cis-prenyltransferase
- drug development
- oxidosqualene
-
ras-transformed
- medicine
-
ras-dependent
-
nonsterols
-
ras-mediated
-
withanolides
- srebp-2
-
ganoderic
- agriculture
- geranylgeraniol
- industry
- cycloartenol
-
non-thiol
- 2,3-oxidosqualene
Reaction
2 (2E,6E)-farnesyl diphosphate + + = + 2 diphosphate +
Synonyms
BbSS, BSS, CrSQS, dt-ySQase, Erg9, EtSS, farnesyl-diphosphate farnesyltransferase, farnesyl-diphosphate:farnesyldiphosphate farnesyltransferase, farnesyldiphosphate farnesyltransferase 1, farnesyldiphosphate:farnesyldiphosphate farnesyltransferase, farnesyltransferase, FDFT1, hSQS, presqualene synthase, presqualene-diphosphate synthase, SgSQS, SQase, SQS, SQS1, SQS2, squalene synthase, squalene synthase 1, squalene synthase 2, squalene synthetase, SS1, SSase, SSN, synthase, squalene, TkSQS1, TkSQS2
ECTree
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Molecular Weight
Molecular Weight on EC 2.5.1.21 - squalene synthase
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39900
Thermosynechococcus vestitus
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x * 42000, SDS-PAGE, x * 41886, electrospray mass spectrometry, x * 39900, calculated
41886
Thermosynechococcus vestitus
-
x * 42000, SDS-PAGE, x * 41886, electrospray mass spectrometry, x * 39900, calculated
42000
Thermosynechococcus vestitus
-
x * 42000, SDS-PAGE, x * 41886, electrospray mass spectrometry, x * 39900, calculated
43000
x * 43000, recombinant C-terminally truncated, His6-tagged WsSQS1and WsSQS2, SDS-PAGE
46000
47000
55000
57000
46000
x * 46000, about, sequence calculation, x * 40000-50000, recombinant enzyme, SDS-PAGE