2.5.1.22: spermine synthase
This is an abbreviated version!
For detailed information about spermine synthase, go to the full flat file.
Word Map on EC 2.5.1.22
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2.5.1.22
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polyamine
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putrescine
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s-adenosylmethionine
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ornithine
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aminopropyltransferases
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snyder-robinson
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alpha-difluoromethylornithine
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acaulis5
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thermospermine
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trans-4-methylcyclohexylamine
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gyro
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kyphoscoliosis
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agriculture
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adometdc
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2.5.1.16
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medicine
- 2.5.1.22
- polyamine
- putrescine
- s-adenosylmethionine
- ornithine
- aminopropyltransferases
-
snyder-robinson
- alpha-difluoromethylornithine
- acaulis5
- thermospermine
- trans-4-methylcyclohexylamine
-
gyro
-
kyphoscoliosis
- agriculture
- adometdc
-
2.5.1.16
- medicine
Reaction
Synonyms
ACL5, aminopropyltransferase, spermidine, OsSPMS1, SMS, spermidine aminopropyltransferase, spermine synthase, spermine synthase 1, spermine synthetase, Spm synthase, SpmS, SPMS1, SpmSyn, synthase, spermine
ECTree
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Expression
Expression on EC 2.5.1.22 - spermine synthase
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knockdown of the MYO5A gene reduces the expression of mRNA coding for spermine synthase. The amount of this transcript is also reduced in cells derived from a patient with Griscelli syndrome type 1. This suggests that, in addition to a direct physical interaction between the two proteins, myosin Va also modulates the transcription of the spermine synthase gene
MYO5A knockdown decreases the expression of spermine synthase gene and renders the distribution of spermine synthase protein diffuse, supporting a role for MyoVa in spermine synthase expression and targeting