2.5.1.39: 4-hydroxybenzoate polyprenyltransferase

This is an abbreviated version!
For detailed information about 4-hydroxybenzoate polyprenyltransferase, go to the full flat file.

Reaction

Synonyms

4-hydroxybenzoate octaprenyl transferase, 4-hydroxybenzoate octaprenyltransferase, 4-hydroxybenzoate polyprenyl diphosphate transferase, 4-hydroxybenzoate transferase, 4-hydroxybenzoate:polyprenyl transferase, 4-hydroxybenzoic acid oligoprenyltransferase, 4-para-hydroxybenzoate:polyprenyl transferase, 4-parahydroxybenzoate: polyprenyl transferase, 4HPT, COQ2, Coq2p, dimethylallyltransferase, p-hydroxybenzoate poly-, nonaprenyl-4-hydroxybenzoate transferase, NPHB transferase, OH-benzoate polyprenyltransferase, ORF3, OsPPT1a, p-hydroxybenzoate dimethylallyltransferase, p-hydroxybenzoate polyprenyltransferase, p-hydroxybenzoate:octaprenyltransferase, p-hydroxybenzoate:polyprenyl transferase, p-hydroxybenzoate:polyprenyltransferase, p-hydroxybenzoic acid-polyprenyl transferase, p-hydroxybenzoic-polyprenyl transferase, para-hydroxybenzoate-polyprenyl transferase, PHB-polyprenyltransferase, polyprenyl 4-hydroxybenzoate transferase, PPT, SmPPT, ubiA

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.39 4-hydroxybenzoate polyprenyltransferase

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Results	in table
26	Activating Compound
17408	AA Sequence
1	Application
1	CAS Registry Number
12	Cloned(Commentary)
1	Crystallization (Commentary)
13	Disease/ Diagnostics
1	Expression
12	General Information
1	General Stability
57	Inhibitors
9	KM Value [mM]
38	Localization
19	Metals/Ions
3	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
45	Organism
16	Pathway
12	pH Optimum
1	pH Range
1	pI Value
20	Protein Variants
1	Purification (Commentary)
2	Reaction
1	Reaction Type
45	Reference
39	Source Tissue
7	Specific Activity [micromol/min/mg]
3	Storage Stability
63	Substrates and Products (Substrate)
3	Subunits
57	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 2.5.1.39 - 4-hydroxybenzoate polyprenyltransferase

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SYSTEMATIC NAME

IUBMB Comments

polyprenyl-diphosphate:4-hydroxybenzoate polyprenyltransferase

This enzyme, involved in the biosynthesis of ubiquinone, attaches a polyprenyl side chain to a 4-hydroxybenzoate ring, producing the first ubiquinone intermediate that is membrane bound. The number of isoprenoid subunits in the side chain varies in different species. The enzyme does not have any specificity concerning the length of the polyprenyl tail, and accepts tails of various lengths with similar efficiency [2,4,5].