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2.5.1.4: adenosylmethionine cyclotransferase

This is an abbreviated version!
For detailed information about adenosylmethionine cyclotransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
=
S-methyl-5'-thioadenosine
+
2-aminobutan-4-olide

Synonyms

adenosylmethioninase, cyclotransferase, adenosylmethionine

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.4 adenosylmethionine cyclotransferase

Inhibitors

Inhibitors on EC 2.5.1.4 - adenosylmethionine cyclotransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5'-O-Methyladenosine
-
weak inhibition
adenine
-
weak inhibition
adenosine
-
weak inhibition
Allo-S-Adenosyl-L-methionine
-
4 mM inhibits more than 50%
dimethyladenosylsulfonium
-
weak inhibition
ethylthioadenosine
-
4 mM inhibits more than 50%
L-methionine
-
weak inhibition
methionine methylsulfonium
-
weak inhibition
methylthioadenosine
-
4 mM inhibits more than 50%
Methylthioinosine
-
weak inhibition
S-adenosyl-L-ethionine
S-adenosyl-L-homocysteine
S-Ribosylmethionine
SH-binding reagents
-
-
-
additional information
-
no effect: Mg2+, EDTA
-