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2.5.1.41: phosphoglycerol geranylgeranyltransferase

This is an abbreviated version!
For detailed information about phosphoglycerol geranylgeranyltransferase, go to the full flat file.

Word Map on EC 2.5.1.41

Reaction

geranylgeranyl diphosphate
+
sn-glycerol 1-phosphate
=
diphosphate
+
3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

Synonyms

((S)-GGGP) synthase, (S)-3-O-geranylgeranylglyceryl phosphate synthase, (S)-3-O-geranylgeranylglycerylphosphate, geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase, geranylgeranyl-transferase, geranylgeranylglycerol-phosphate geranylgeranyltransferase, geranylgeranylglyceryl phosphate synthase, geranylgeranyltransferase II, geranylgeranyltransferase, geranylgeranyloxyglycerol phosphate, GGGP synthase, GGGPS, glycerol phosphate feranylgeranyltransferase, prenyltransferase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.41 phosphoglycerol geranylgeranyltransferase

Reference

Reference on EC 2.5.1.41 - phosphoglycerol geranylgeranyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zhang, D.L.; Daniels, L.; Poulter, C.D.
Biosynthesis of archaebacterial membranes. Formation of isoprene ethers by a prenyl transfer reaction
J. Am. Chem. Soc.
112
1264-1265
1990
Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus Marburg / DSM 2133
-
Manually annotated by BRENDA team
Payandeh, J.; Fujihashi, M.; Gillon, W.; Pai, E.F.
The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme
J. Biol. Chem.
281
6070-6078
2006
Archaeoglobus fulgidus
Manually annotated by BRENDA team
Nemoto, N.; Oshima, T.; Yamagishi, A.
Purification and characterization of geranylgeranylglyceryl phosphate synthase from a thermoacidophilic archaeon, Thermoplasma acidophilum
J. Biochem.
133
651-657
2003
Thermoplasma acidophilum
Manually annotated by BRENDA team
Chen, A.; Zhang, D.; Poulter, C.
(S)-geranylgeranylglyceryl phosphate synthase. Purification and characterization of the first pathway-specific enzyme in archaebacterial membrane lipid biosynthesis
J. Biol. Chem.
268
21701-21705
1993
Methanothermobacter thermautotrophicus
Manually annotated by BRENDA team
Villanueva, L.; Schouten, S.; Sinninghe Damste, J.S.
Depth-related distribution of a key gene of the tetraether lipid biosynthetic pathway in marine Thaumarchaeota
Environ. Microbiol.
17
3527-3539
2015
Thaumarchaeota
Manually annotated by BRENDA team
Blank, P.N.; Barnett, A.A.; Ronnebaum, T.A.; Alderfer, K.E.; Gillott, B.N.; Christianson, D.W.; Himmelberger, J.A.
Structural studies of geranylgeranylglyceryl phosphate synthase, a prenyltransferase found in thermophilic Euryarchaeota
Acta Crystallogr. Sect. D
76
542-557
2020
Thermoplasma volcanium (Q97AR4), Thermoplasma volcanium, Thermoplasma volcanium ATCC 51530 (Q97AR4)
Manually annotated by BRENDA team
Nemoto, N.; Miyazono, K.I.; Tanokura, M.; Yamagishi, A.
Crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase from Thermoplasma acidophilum in complex with the substrate sn-glycerol 1-phosphate
Acta Crystallogr. Sect. F
75
470-479
2019
Thermoplasma acidophilum (Q9HJH3), Thermoplasma acidophilum, Thermoplasma acidophilum ATCC 25905 (Q9HJH3)
Manually annotated by BRENDA team
Linde, M.; Heyn, K.; Merkl, R.; Sterner, R.; Babinger, P.
Hexamerization of geranylgeranylglyceryl phosphate synthase ensures structural integrity and catalytic activity at high temperatures
Biochemistry
57
2335-2348
2018
Methanothermobacter thermautotrophicus (O26652), Methanothermobacter thermautotrophicus, Methanothermobacter thermautotrophicus ATCC 29096 (O26652)
Manually annotated by BRENDA team