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2.5.1.43: nicotianamine synthase

This is an abbreviated version!
For detailed information about nicotianamine synthase, go to the full flat file.

Word Map on EC 2.5.1.43

Reaction

3 S-adenosyl-L-methionine = 3 S-methyl-5'-thioadenosine +

nicotianamine

Synonyms

AtNAS, AtNAS1, AtNAS2, AtNAS3, AtNAS4, chloronerva, HvNAS1, HvNAS2, HvNAS3, HvNAS4, HvNAS6, HvNAS7, HvNAS8, HvNAS9, LeNAS, LjNAS1, LjNAS2, MtNAS, MxNAS2, NA synthase, NA synthase 2, NAS, NAS1, NAS2, NAS3, NAS4, NASHOR1, NASHOR2, nicotianamine synthase, nicotianamine synthase 1, nicotianamine synthase 2, nicotianamine synthase 4, OsNA S2, OsNAS1, OsNAS2, OsNAS3, S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase, synthase, nicotianamine, TaNAS1, TaNAS1-A, TaNAS1-B, TaNAS2, TaNAS2-A, TaNAS2-D1, TaNAS2-D2, TaNAS3-A, TaNAS3-B, TaNAS4-A, TaNAS4-D, TaNAS4-U, TaNAS5-B, TaNAS6-A, TaNAS6-B, TaNAS6-D, TaNAS7-A1, TaNAS7-A2, TaNAS7-D, TaNAS9-A, TaNAS9-B, TaNAS9-D, TmNAS, TmNAS1, TmNAS2, TmNAS3, TmNAS4, TmNAS5, TmNAS6, TmNAS7, TmNAS8, ZmNAS1, ZmNAS10, ZmNAS1;1, ZmNAS1;2, ZmNAS2, ZmNAS2;1, ZmNAS2;2, ZmNAS3, ZmNAS4, ZmNAS5, ZmNAS6, ZmNAS6;1, ZmNAS6;2, ZmNAS7, ZmNAS8, ZmNAS9

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.43 nicotianamine synthase

Expression

Expression on EC 2.5.1.43 - nicotianamine synthase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
a significant increase of nicotianamine Synthase (NAS3) gene transcription is induced by the 400 mg/kg and 800 mg/kg of nickel nitrate doses compared to water. This upregulation was driven by nitrate rather than nickel. The low level of bioavailable nickel in metal-contaminated soils (less than 150 mg/kg) cannot induce differential transcription of NAS3
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all ZmNAS genes are responsive to heavy metal ions (Ni, Fe, Cu, Mn, Zn, and Cd). ZmNAS gene expression of maize seedlings is regulated by jasmonic acid, abscisic acid, and salicylic acid
class I ZmNAS genes are induced under Fe deficiency and are suppressed under Fe excessive conditions, while the expression pattern of class II genes are opposite to class I. Expression patterns of ZmNAS genes in response to fluctuating metal status
class I ZmNAS genes are induced under Fe deficiency and are suppressed under Fe excessive conditions, while the expression pattern of class II genes are opposite to class I. Expression patterns of ZmNAS genes in response to fluctuating metal status. Class I genes are suppressed in response to Zn excess and Cu/Mn deficiency
class I ZmNAS genes are induced under Fe deficiency and are suppressed under Fe excessive conditions, while the expression pattern of class II genes are opposite to class I. Expression patterns of ZmNAS genes in response to fluctuating metal status. Class I ZmNAS genes are stimulated under Zn deficiency
class I ZmNAS genes are induced under Fe deficiency and are suppressed under Fe excessive conditions, while the expression pattern of class II genes are opposite to class I. Expression patterns of ZmNAS genes in response to fluctuating metal status. Class II genes are induced under excessive Zn and deficient Cu/Mn conditions
expression level of nicotianamine synthase TmNAS1 shows a downward trend under Fe-sufficient growth conditions
expression level of nicotianamine synthase TmNAS2 shows a downward trend under Fe-sufficient growth conditions
expression level of nicotianamine synthase TmNAS3 shows a downward trend under Fe-sufficient growth conditions
expression level of nicotianamine synthase TmNAS4 shows a downward trend under Fe-sufficient growth conditions
expression level of nicotianamine synthase TmNAS5 shows a downward trend under Fe-sufficient growth conditions
expression level of nicotianamine synthase TmNAS6 shows a downward trend under Fe-sufficient growth conditions
expression level of nicotianamine synthase TmNAS7 shows that a downward trend begins to emerge from day 4 under Fe-sufficient growth conditions
expression level of nicotianamine synthase TmNAS8 shows a downward trend under Fe-sufficient growth conditions
expression of the clade I TaNAS genes (TaNAS3-A, TaNAS1-A, TaNAS3-B, TaNAS1-B, TaNAS5-B, TaNAS6-A, TaNAS6-B, TaNAS6-D, TaNAS4-A, TaNAS7-A2, TaNAS7-A1, TaNAS2-A, TaNAS7-D, TaNAS2-D1, TaNAS2-D2TaNAS4-D, TaNAS4-U) is significantly up-regulated in root tissues with approximately 15fold higher expression at day 5 and threefold higher expression at day 7 of the treatment relative to control
expression of the clade I Triticum aestivum nicotianamine synthase genes (TaNAS3-A, TaNAS1-A, TaNAS3-B, TaNAS1-B, TaNAS5-B, TaNAS6-A, TaNAS6-B, TaNAS6-D, TaNAS4-A, TaNAS7-A2, TaNAS7-A1, TaNAS2-A, TaNAS7-D, TaNAS2-D1, TaNAS2-D2TaNAS4-D, TaNAS4-U) is significantly up-regulated in root tissues with approximately 15fold higher expression at day 5 and threefold higher expression at day 7 of the treatment relative to control
expression of the clade I Triticum aestivum nicotianamine synthase genes (TaNAS3-A, TaNAS1-A, TaNAS3-B, TaNAS1-B, TaNAS5-B, TaNAS6-A, TaNAS6-B, TaNAS6-D, TaNAS4-A, TaNAS7-A2, TaNAS7-A1, TaNAS2-A, TaNAS7-D, TaNAS2-D1, TaNAS2-D2TaNAS4-D, TaNAS4-U) is significantly up-regulated in root tissues with approximately 15fold higher expression at day 5 and threefold higher expression at day 7 of the treatment relative to controlsy
in leaves and roots, NAS4 were up-regulated 2- to 3fold by Ni treatment
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in leaves, NAS3 is up-regulated 3fold by Ni treatment
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in roots, NAS1 is up-regulated twice by Ni treatment
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iron deficiency markedly increases expression of NAS4 in leaves
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iron deficiency significantly decreases expression of NAS3 in leaves
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iron deficiency slightly increases expression of NAS2 in roots
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OsNAS2 is iron deficiency-inducible, while Zn-, Cu-, and Mn-deficiencies have no effect on the gene expression
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strongly induced with excess Fe in most rice tissues, particularly old leaves, suggesting that it may play a vital role under excess Fe conditions
the expression of MxNAS2 is highly affected by Fe stress and indoleacetic acid treatment, whereas, weakly affected by abscisic acid treatment in seedlings
the expression of TaNAS1 and TaNAS2 are rapidly upregulated by increasing N supplied level in roots and leaves
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ZmNAS gene expression of maize seedlings is regulated by jasmonic acid, abscisic acid, and salicylic acid
ZmNAS1 gene is suppressed by heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd
ZmNAS10 is downregulated by Ni
ZmNAS2 gene is suppressed by heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd
ZmNAS3 gene is uppressed by heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd
ZmNAS4 gene is induced by heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd
ZmNAS5 is downregulated by Cd, Cu, Ni, and Mn
ZmNAS6 is downregulated by Ni
ZmNAS7 gene is induced by Fe
ZmNAS7 is downregulated by Cu and Ni
ZmNAS8 gene is responsive to heavy metal ions Ni, Fe, Cu, Mn, Zn, and Cd
ZmNAS9 is downregulated by Ni, Mn, Fe, and Zn