Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.5.1.46: deoxyhypusine synthase

This is an abbreviated version!
For detailed information about deoxyhypusine synthase, go to the full flat file.

Word Map on EC 2.5.1.46

Reaction

dehydrospermidine
+
[enzyme]-lysine
=
N-(4-aminobutylidene)-[enzyme]-lysine
+
propane-1,3-diamine

Synonyms

CpDHS, deoxyhypusine synthase, deoxyhypusine synthase (Caulobacter crescentus gene CC0359), deoxyhypusine synthase (Halobacterium strain NRC-1 gene dhs), deoxyhypusine synthase (human clone 30649 gene DHPS subunit reduced), deoxyhypusine synthase (Nicotiana tabacum gene DHS1), deoxyhypusine synthase (Senecio vernalis gene DHS1), deoxyhypusinesynthase, DHPS, DHS, DHS1, DHS2, DHS20, DHS34, DHSc, DHSp, DHYS, Dys1, Dys1p, EC 1.1.1.249, HVO 2297, PF3D7_1412600, speY, synthase, deoxyhypusine, TbDHSc, TbDHSp

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.46 deoxyhypusine synthase

Cloned

Cloned on EC 2.5.1.46 - deoxyhypusine synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DHS DNA and amino acid seuence determination and analysis, functional coexpression with human deoxyhypusine hydroxylase and human eukaryotic translation initiation factor 5A in Escherichia coli strain BL21(DE3)pLys that produces eIF5A(Hpu), overview
-
DHS gene, DNA and amino acid sequence determination and analysis
DHSL20 is a DHS-like gene from chromosome 20 and DHS34, a DHS gene from chromosome 34, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, expression of His-tagged DHSL20 and DHS34 in Escherichia coli
expressed as a C-terminal his-tagged fusion protein
expressed in Escherichia coli as a His-tagged fusion protein
expression in Escherichia coli
expression in Escherichia coli, the deduced amino acid sequence shows a high degree of identity to that of yeast enzyme and to the known sequences of tryptic peptides from the rat and Neurospora enzymes
gene DHPS, DHPS is a metastasis-associated gene within the specific amplification at chromosome 19p13.2–p13.13 in HOC313-LM cells, quantitative RT-PCR expressionanalysis
gene DHS, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21(DE3)
gene DHS, located on chromosome 2, DNA and amino acid sequence determination and analysis, sequence comparisons, recombinant expression of soluble His-tagged enzyme in Escherichia coli strain Rosetta (DE3)
gene dhs, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21-CodonPlus (DE3), coexpression with His-tagged DOHH (deoxyhypusine hydroxylase) in Escherichia coli strain BL21-CodonPlus (DE3), quantitative real-time PCR expression analysis
gene dhs, single-copy gene, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, analysis of gene duplications in Convolvulaceae species
gene DHS, targeted enzyme overexpression in Fusarium graminearum by single crossover event inserting the linearized vector pMW-DHS
gene Tb10.70.4900, DNA and amino acid sequence determination and analysis, sequence comparisons, phylogenetic analysis, recombinant expression of N-terminally His6-tagged enzyme in Escherichia coli strain BL21 (DE3), coexpression with gene TB927.1.870 results in heterotetramer formation with a 3000fold increase in enzyme activity
gene TB927.1.870, DNA and amino acid sequence determination and analysis, sequence comparisons, phylogenetic analysis, recombinant expression of N-terminally His6-tagged enzyme in Escherichia coli strain BL21 (DE3), coexpression with gene Tb10.70.4900 in Escherichia coli strain BL21 (DE3) results in heterotetramer formation with a 3000fold increase in enzyme activity
gene TvDHS, DNA and amino acid sequence determination and analysis, genetic organization, sequence comparisons and phylogenetic tree, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21(DE3), coexpression with recombinant TveIF-5A (rTveIF-5A) precursor protein and formation of a TvDHS-TveIF-5A complex
subcloning of bovine and human DHS gene, overexpression in Escherichia coli
transgenic canola lines with suppressed DHS expression were obtained by introducing a transgene expressing antisense 3'-UTR canola deoxyhypusine synthase cDNA under the regulation of the constitutive cauliflower mosaic virus 35S (CaMV-35S) promoter
-